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自闭症谱系障碍儿童眼部检查结果评估:观察性研究。

Evaluation of ocular findings in children with autism spectrum disorder: Observational study.

作者信息

Demir Ulku

机构信息

Department of Ophthalmology, Inonu University Faculty of Medicine, Malatya, Turkey.

出版信息

Medicine (Baltimore). 2025 Jul 18;104(29):e43398. doi: 10.1097/MD.0000000000043398.

Abstract

This study aims to emphasize the significance of ophthalmologic examination in children with autism spectrum disorder (ASD) and evaluate the ophthalmologic findings and their frequency. We retrospectively analyzed the files of 40 boys and 20 girls aged 4 to 18. In cycloplegic spherical equivalents, -0.50 diopter (D) or more myopia, ≥+2.0D hyperopia and ≥±1D astigmatism in cylindrical equivalents were accepted. Patients with ≥1D difference in spherical or cylindrical equivalents between the 2 eyes were considered anisometropic. Amblyopia was defined as a best-corrected visual acuity ≤0.8 with Snellen chart and a difference of at least 2 lines between both eyes. Children were grouped as myopia, hyperopia, myopia astigmatism, hyperopia astigmatism, mixed astigmatism, emmetrope and anisometropia according to refractive errors. Strabismus was classified as esotropia, exotropia and orthophoric. Forty (66.66%) of the patients with ASD were boys and 20 (33.33%) were girls. Emmetropia was found in 38.33%, myopia in 3.33%, hyperopia in 21.66%, myopia astigmatism in 16.66%, hyperopia astigmatism in 14.99%, mixed astigmatism in 1.66%, anisometropia in 6.66%, amblyopia in 6.66%, esotropia in 9.99%, exotropia in 11.66%, ptosis in 4.99%, and nystagmus in 1.66%. There was no statistically significant difference in the findings except hyperopia according to gender (P > .05). Hyperopia (P = .022) showed a statistically significant difference according to gender (P < .05). Children with ASD have significant ophthalmological abnormalities. Early diagnosis and treatment of refractive errors and other eye problems may contribute to these children's psychomotor and social development.

摘要

本研究旨在强调眼科检查在自闭症谱系障碍(ASD)儿童中的重要性,并评估眼科检查结果及其出现频率。我们回顾性分析了40名男孩和20名年龄在4至18岁女孩的病历。在睫状肌麻痹下的等效球镜度数方面,-0.50屈光度(D)或更高的近视、≥+2.0D的远视以及等效柱镜度数≥±1D的散光被纳入研究范围。双眼等效球镜或柱镜度数相差≥1D的患者被视为屈光参差。弱视的定义为使用斯内伦视力表时最佳矫正视力≤0.8且双眼视力相差至少2行。根据屈光不正情况,儿童被分为近视、远视、近视散光、远视散光、混合散光、正视和屈光参差组。斜视分为内斜视、外斜视和正位。40名(66.66%)患有ASD的患者为男孩,20名(33.33%)为女孩。正视占38.33%,近视占3.33%,远视占21.66%,近视散光占16.66%,远视散光占14.99%,混合散光占1.66%,屈光参差占6.66%,弱视占6.66%,内斜视占9.99%,外斜视占11.66%,上睑下垂占4.99%,眼球震颤占1.66%。除远视外,其他检查结果在性别上无统计学显著差异(P>0.05)。远视(P=0.022)在性别上显示出统计学显著差异(P<0.05)。患有ASD的儿童存在明显的眼科异常。屈光不正和其他眼部问题的早期诊断和治疗可能有助于这些儿童的心理运动和社交发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f6/12282795/5e411cb8ac6e/medi-104-e43398-g001.jpg

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