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Weight management in overweight or obesity: Implications for cancer pathogenesis and prognosis.

作者信息

Wang Yue, Niu Haitao, Lyu Peng, Liu Bing, Wei Junmin

机构信息

National Institutes for Food and Drug Control, Beijing 102629, China.

National Health Commission of the People's Republic of China, Beijing 100044, China.

出版信息

Cancer Pathog Ther. 2025 May 9;3(4):273-275. doi: 10.1016/j.cpt.2025.05.001. eCollection 2025 Jul.

DOI:10.1016/j.cpt.2025.05.001
PMID:40697516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12277812/
Abstract
摘要

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Lancet. 2025 Mar 8;405(10481):813-838. doi: 10.1016/S0140-6736(25)00355-1. Epub 2025 Mar 3.
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The GLP-1R agonist semaglutide reshapes pancreatic cancer associated fibroblasts reducing collagen proline hydroxylation and favoring T lymphocyte infiltration.胰高血糖素样肽-1受体激动剂司美格鲁肽重塑胰腺癌相关成纤维细胞，减少胶原蛋白脯氨酸羟化并促进T淋巴细胞浸润。
J Exp Clin Cancer Res. 2025 Jan 20;44(1):18. doi: 10.1186/s13046-024-03263-w.
3
Relationship between visceral obesity and prognosis in patients with stage IVB cervical cancer receiving radiotherapy and chemotherapy.IVB期宫颈癌患者接受放化疗时内脏肥胖与预后的关系
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Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021.204 个国家和地区 2022-2050 年疾病负担情景：2021 年全球疾病负担研究的预测分析。
Lancet. 2024 May 18;403(10440):2204-2256. doi: 10.1016/S0140-6736(24)00685-8.
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.全球疾病负担研究 2021 年在 204 个国家和地区、811 个次国家级地点对 88 种风险因素的全球负担和证据强度：系统分析。
Lancet. 2024 May 18;403(10440):2162-2203. doi: 10.1016/S0140-6736(24)00933-4.
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Obesity-related T cell dysfunction impairs immunosurveillance and increases cancer risk.肥胖相关的 T 细胞功能障碍会损害免疫监视并增加癌症风险。
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