McCaffrey R J
Physiol Behav. 1985 Aug;35(2):151-6. doi: 10.1016/0031-9384(85)90329-4.
The appropriateness of kaolin consumption, one form of pica, as an index of motion sickness in the rat was examined. Unlike other motion sickness indices, the use of kaolin consumption results in a bitonic function across daily rotation sessions. This bitonic function is not predicted from any theory of motion sickness (viz., the Sensory Rearrangement Theory), rather an inverse relationship should exist between the severity of motion sickness and repeated exposure to the effective motion (i.e., habituation). The results of Experiments 1 and 2 support the continued use of kaolin consumption as an index of motion sickness in the rat. A response interference process is proposed to account for the first portion of the bitonic kaolin consumption function with grooming possibly representing a higher probability behavior than kaolin consumption. Experiment 3 examined and confirmed that kaolin consumption indexes the process of rehabituation to an effective motion. This extends the number of principles that are characteristic of motion sickness exhibited by species capable of emesis and supports the continued use of kaolin consumption as an index of motion sickness and general gastrointestinal malaise in the rat.
研究了高岭土摄入（异食癖的一种形式）作为大鼠晕动病指标的适用性。与其他晕动病指标不同，使用高岭土摄入量会在每日旋转试验中产生双调函数。这种双调函数无法从任何晕动病理论（即感觉重新排列理论）中预测出来，相反，晕动病的严重程度与反复暴露于有效运动（即习惯化）之间应该存在反比关系。实验1和2的结果支持继续将高岭土摄入量用作大鼠晕动病的指标。提出了一种反应干扰过程来解释双调高岭土摄入函数的第一部分，梳理行为可能比高岭土摄入更具发生概率。实验3检验并证实了高岭土摄入量可作为对有效运动重新适应过程的指标。这扩展了能够呕吐的物种所表现出的晕动病特征的原理数量，并支持继续将高岭土摄入量用作大鼠晕动病和一般胃肠不适的指标。
