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大鼠晕动病诱发的异食癖。

Motion sickness-induced pica in the rat.

作者信息

Mitchell D, Laycock J D, Stephens W F

出版信息

Am J Clin Nutr. 1977 Feb;30(2):147-50. doi: 10.1093/ajcn/30.2.147.

DOI:10.1093/ajcn/30.2.147
PMID:556878
Abstract

Two experiments investigating the effects of motion sickness on pica (the consumption of non-nutritive substances) are reported. In the first experiment rats subject to rotational stimulation subsequently engaged in geophagia (clay consumption). In the second experiment use of a conditioned aversion paradigm confirmed that the method of rotational stimulation used in the first experiment causes motion sickness in rats. The results of these experiments indicate that simple gastrointestinal malaise in the absence of a deficiency state or acute toxemia will elicit pica. It is suggested that gastrointestinal distress may be a significant factor in the etiology of pica and its relationship to other causes of pica is discussed.

摘要

本文报告了两项关于晕动病对异食癖(食用非营养性物质)影响的实验。在第一个实验中,遭受旋转刺激的大鼠随后出现了食土癖(食用黏土)。在第二个实验中,使用条件性厌恶范式证实了第一个实验中使用的旋转刺激方法会使大鼠产生晕动病。这些实验结果表明,在没有营养缺乏状态或急性毒血症的情况下,单纯的胃肠道不适会引发异食癖。研究表明,胃肠道不适可能是异食癖病因中的一个重要因素,并对其与异食癖其他病因的关系进行了讨论。

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Am J Clin Nutr. 1977 Feb;30(2):147-50. doi: 10.1093/ajcn/30.2.147.
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