Weippert Matthias, Behrens Martin, Schlegel Martin, Schröder Tom, Tillmann Moritz, Rühe Nelly, Römer Robert, Mau-Möller Anett, Bruhn Sven
University of Rostock, Institute of Sport Science, Rostock, Germany.
University of Applied Sciences for Sport and Management Potsdam, Potsdam, Germany.
J Int Soc Sports Nutr. 2025 Dec;22(1):2534131. doi: 10.1080/15502783.2025.2534131. Epub 2025 Jul 24.
Caffeine has been shown to improve endurance performance probably primary due to its pharmacological effects in the central nervous system modifying, among others, the perceptual responses during exercise. However, most studies proving the performance-enhancing effects of caffeine utilized an experimental caffeine restriction phase prior to the measurement sessions. Therefore, the effects of 2.5 and 6 mg*kg oral caffeine ingestion on endurance performance, perceptual, affective, and cognitive responses during exercise, as well as time perception, were investigated in participants following their normal "ad libitum" daily diet.
Two double-blinded, randomized placebo-controlled cross-over studies were performed to test the effect of 2.5 ( = 35, age: 23.3 ± 3.5 years, habitual caffeine consumption of 106 ± 89 mgday) and 6.0 mgkg ( = 21, age: 21.2 ± 2.3 years, habitual caffeine consumption of 87 ± 64 mg*day) oral caffeine ingestion on time to exhaustion (TTE), perceived fatigue, perceptual-discriminatory (effort perception, physical strain), affective-motivational (affective valence, arousal, dominance, motivation, boredom), and cognitive-evaluative responses (decisional conflict, attentional focus) as well as time perception (time production and estimation) and heart rate during cycling at 65% peak power. Participants were low-to-moderate caffeine consumers (one participant in each study reported no habitual caffeine intake) and asked to follow their regular "ad libitum" diet without any restrictions regarding caffeinated beverages and/or food during the studies.
Neither a dose of 2.5 nor of 6.0 mg*kg was found to be superior to placebo with respect to TTE, perceived fatigue, the perceptual-discriminatory, affective-motivational, and cognitive-evaluative responses to exercise, as well as time perception.
Both dosages of caffeine had no effect on TTE, perceived fatigue, perceptual-discriminatory, affective-motivational, and cognitive-evaluative responses to exercise, as well as on time perception and heart rate in low-to-moderate caffeine consumers without a prior experimental caffeine restriction phase. The findings suggest that caffeine´s positive effects on endurance performance and perceptual responses to exercise found in previous studies might be partly explained by the reversal of adverse effects induced by a prior caffeine restriction phase.
咖啡因已被证明可提高耐力表现,这可能主要归因于其对中枢神经系统的药理作用,其中包括改变运动过程中的感知反应等。然而,大多数证明咖啡因具有提高运动表现作用的研究在测量阶段之前都采用了实验性的咖啡因限制期。因此,本研究在参与者按照其正常“随意”日常饮食的情况下,探究了口服2.5毫克/千克和6毫克/千克咖啡因对耐力表现、运动过程中的感知、情感和认知反应以及时间感知的影响。
进行了两项双盲、随机、安慰剂对照的交叉研究,以测试2.5毫克/千克(n = 35,年龄:23.3±3.5岁,习惯性咖啡因摄入量为106±89毫克/天)和6.0毫克/千克(n = 21,年龄:21.2±2.3岁,习惯性咖啡因摄入量为87±64毫克/天)口服咖啡因对力竭时间(TTE)、感知疲劳、感知辨别(努力感知、身体应变)、情感动机(情感效价、唤醒、支配、动机、无聊)和认知评估反应(决策冲突、注意力焦点)以及时间感知(时间产生和估计)和在65%峰值功率下骑行时心率的影响。参与者为低至中度咖啡因消费者(每项研究中有一名参与者报告无习惯性咖啡因摄入),并要求他们在研究期间遵循常规“随意”饮食,对含咖啡因的饮料和/或食物没有任何限制。
在TTE、感知疲劳、对运动的感知辨别、情感动机和认知评估反应以及时间感知方面,未发现2.5毫克/千克或6.0毫克/千克的剂量优于安慰剂。
在没有先前实验性咖啡因限制期的低至中度咖啡因消费者中,两种剂量的咖啡因对TTE、感知疲劳、对运动的感知辨别、情感动机和认知评估反应以及时间感知和心率均无影响。研究结果表明,先前研究中发现的咖啡因对耐力表现和运动感知反应的积极作用可能部分归因于先前咖啡因限制期所诱导的不良反应的逆转。