De Broucker T, Willer J C
Rev Electroencephalogr Neurophysiol Clin. 1985 Sep;15(2):149-53. doi: 10.1016/s0370-4475(85)80019-8.
A study was carried out with 10 normal volunteers in order to find a correlation between nociceptive flexion reflexes from the biceps femoris muscle and the amplitude of the late component (N150-P220) of the vertex evoked potential elicited by sural nerve stimulations at various intensities randomly delivered. The range of stimulus varied from the perception threshold (usually 1 mA) to 2 times the reflex threshold. This latter parameter was usually found between 8 and 11 mA. While the nociceptive flexion reflex increased linearly as a function of stimulation intensity, the amplitude of N150-P220 was maximum at pain threshold and remained in plateau at this level or even slightly decreased as a function of stimulus intensity. No significant correlation was found between the recruitment curve of the nociceptive reflex and that of the late component of the evoked potential as a function of stimulus intensity. Functional implications of these data are discussed.
对10名正常志愿者进行了一项研究，目的是找出股二头肌的伤害性屈曲反射与不同强度的腓肠神经刺激诱发的顶点诱发电位晚期成分（N150 - P220）的幅度之间的相关性。刺激范围从感觉阈值（通常为1毫安）到反射阈值的2倍。后一个参数通常在8至11毫安之间。虽然伤害性屈曲反射随刺激强度呈线性增加，但N150 - P220的幅度在疼痛阈值时最大，并在该水平保持平稳，甚至随刺激强度略有下降。未发现伤害性反射的募集曲线与诱发电位晚期成分的募集曲线之间存在与刺激强度相关的显著相关性。讨论了这些数据的功能意义。
