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疾病概率增强的随访胸部X光放射学报告摘要生成

Disease probability-enhanced follow-up chest X-ray radiology report summary generation.

作者信息

Wang Zhichuan, Deng Qiao, So Tiffany Y, Chiu Wan Hang, Lee Kinhei, Hui Edward S

机构信息

Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, HKSAR, China.

The CU Lab for AI in Radiology (CLAIR), The Chinese University of Hong Kong, HKSAR, China.

出版信息

Sci Rep. 2025 Jul 24;15(1):26930. doi: 10.1038/s41598-025-12684-2.

DOI:10.1038/s41598-025-12684-2
PMID:40707613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12289907/
Abstract

A chest X-ray radiology report describes abnormal findings not only from X-ray obtained at a given examination, but also findings on disease progression or change in device placement with reference to the X-ray from previous examination. Majority of the efforts on automatic generation of radiology report pertain to reporting the former, but not the latter, type of findings. To the best of the authors' knowledge, there is only one work dedicated to generating summary of the latter findings, i.e., follow-up radiology report summary. In this study, we propose a transformer-based framework to tackle this task. Motivated by our observations on the significance of medical lexicon on the fidelity of report summary generation, we introduce two mechanisms to bestow clinical insight to our model, namely disease probability soft guidance and masked entity modeling loss. The former mechanism employs a pretrained abnormality classifier to guide the presence level of specific abnormalities, while the latter directs the model's attention toward medical lexicon. Extensive experiments were conducted to demonstrate that the performance of our model exceeded the state-of-the-art.

摘要

一份胸部X光放射学报告不仅描述了在特定检查中获得的X光的异常发现,还参照先前检查的X光描述了疾病进展或设备放置变化的发现。自动生成放射学报告的大部分工作都致力于报告前一种发现,而不是后一种发现。据作者所知,只有一项工作致力于生成后一种发现的总结,即随访放射学报告总结。在本研究中,我们提出了一个基于Transformer的框架来解决这个任务。基于我们对医学词汇对报告总结生成保真度的重要性的观察,我们引入了两种机制来赋予我们的模型临床洞察力,即疾病概率软引导和掩码实体建模损失。前一种机制采用预训练的异常分类器来指导特定异常的存在水平,而后一种机制将模型的注意力引向医学词汇。进行了广泛的实验以证明我们模型的性能超过了现有技术水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/73276104ac79/41598_2025_12684_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/71b51ddb1f35/41598_2025_12684_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/a96c9d3cf2a3/41598_2025_12684_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/2938a8476c5a/41598_2025_12684_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/ff56d86787cd/41598_2025_12684_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/9c11c5042950/41598_2025_12684_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/73276104ac79/41598_2025_12684_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/71b51ddb1f35/41598_2025_12684_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/a96c9d3cf2a3/41598_2025_12684_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/2938a8476c5a/41598_2025_12684_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/ff56d86787cd/41598_2025_12684_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/9c11c5042950/41598_2025_12684_Figb_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e265/12289907/73276104ac79/41598_2025_12684_Fig4_HTML.jpg

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本文引用的文献

1
Memory-Based Cross-Modal Semantic Alignment Network for Radiology Report Generation.用于放射学报告生成的基于记忆的跨模态语义对齐网络
IEEE J Biomed Health Inform. 2024 Jul;28(7):4145-4156. doi: 10.1109/JBHI.2024.3393018. Epub 2024 Jul 2.
2
CAMANet: Class Activation Map Guided Attention Network for Radiology Report Generation.CAMANet:用于生成放射学报告的类激活映射引导注意力网络
IEEE J Biomed Health Inform. 2024 Jan 16;PP. doi: 10.1109/JBHI.2024.3354712.
3
A Novel Deep Learning Model for Medical Report Generation by Inter-Intra Information Calibration.
一种通过内外信息校准生成医学报告的新型深度学习模型。
IEEE J Biomed Health Inform. 2023 Oct;27(10):5110-5121. doi: 10.1109/JBHI.2023.3236661. Epub 2023 Oct 5.
4
Prior Guided Transformer for Accurate Radiology Reports Generation.预先引导的转换器,用于生成准确的放射学报告。
IEEE J Biomed Health Inform. 2022 Nov;26(11):5631-5640. doi: 10.1109/JBHI.2022.3197162. Epub 2022 Nov 10.
5
MIMIC-CXR, a de-identified publicly available database of chest radiographs with free-text reports.MIMIC-CXR,一个去标识化的、公开可用的、包含自由文本报告的胸部 X 光数据库。
Sci Data. 2019 Dec 12;6(1):317. doi: 10.1038/s41597-019-0322-0.