Wang Siyuan, Sun Jingjie, Xu Zhiwei, Di Tanna Gian Luca, Chen Mingsheng, Downey Laura E, Jan Stephen, Si Lei
The George Institute for Global Health, University of New South Wales, Sydney, Australia.
Shandong Health Commission Medical Management Service Center, Jinan, China.
J Glob Health. 2025 Jul 25;15:04218. doi: 10.7189/jogh.15.04218.
Multiple chronic conditions are imposing an increasing health and economic burden on the Chinese health system. While exposure to residential greenness has been shown to provide various health benefits, its relationship with multiple chronic conditions remains largely unexplored. This study aims to investigate this relationship using high-resolution satellite imagery and data from the 6th Health Services Survey (HSS) cohort in Shandong province.
We linked health data from the HSS with 12-month average Normalised Difference Vegetation Index (NDVI) measurements based on reported residential geocodes. Multiple chronic condition status was defined as having two or more chronic conditions concurrently, according to the HSS's predefined disease classification. Generalised mixed regression models were utilised to assess both the likelihood and count of multiple chronic conditions in relation to greenspace exposure. Additionally, using the pre-defined disease classes, we also explored how greenspace influences multiple chronic conditions across various physiological systems and disease categories.
A total of 28 489 individuals were included in this cross-sectional analysis. After adjusting for potential confounding factors, we found that exposure to greenspace was significantly associated with a reduced prevalence and count of chronic conditions. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for were: Q2 (aOR = 0.74; 95% CI = 0.62, 0.88), Q3 (aOR = 0.69; 95% CI = 0.55, 0.86), and Q4 (aOR = 0.70; 95% CI = 0.56, 0.88), respectively, compared against the baseline Q1 quartile. Subgroup analyses revealed that higher residential greenspace exposure reduced risks of blood, endocrine, nutritional and metabolic chronic diseases. No clear associations were found for other chronic disease classes. Additionally, consistent results were observed across spatial and temporal sensitivity analyses.
Our findings underscore the potential beneficial effects of residential greenness on multiple chronic conditions, with implications for urban planning, environmental policy, and community development.
多种慢性疾病给中国卫生系统带来了日益沉重的健康和经济负担。虽然已证明接触居住环境中的绿色空间对健康有诸多益处,但其与多种慢性疾病的关系在很大程度上仍未得到充分探索。本研究旨在利用高分辨率卫星图像以及山东省第六次卫生服务调查(HSS)队列的数据来调查这种关系。
我们将HSS的健康数据与基于报告的居住地理编码的12个月平均归一化植被指数(NDVI)测量值相链接。根据HSS预先定义的疾病分类,多种慢性疾病状态被定义为同时患有两种或更多种慢性疾病。使用广义混合回归模型来评估与绿色空间暴露相关的多种慢性疾病的可能性和数量。此外,利用预先定义的疾病类别,我们还探讨了绿色空间如何影响各个生理系统和疾病类别的多种慢性疾病。
本横断面分析共纳入28489名个体。在调整潜在混杂因素后,我们发现接触绿色空间与慢性病患病率和数量的降低显著相关。与基线第一四分位数相比,第二四分位数(调整后的优势比[aOR]=0.74;95%置信区间[CI]=0.62,0.88)、第三四分位数(aOR=0.69;95%CI=0.55,0.86)和第四四分位数(aOR=0.70;9