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蚊媒虫媒病毒综合研究议程会议报告

Meeting Report on an Integrated Research Agenda for Mosquito-Borne Arboviruses.

作者信息

Ulrich Angela K, Moua Nicolina M, Mack Alison, Imai-Eaton Natsuko, Staples J Erin, Mehr Angela J, Ostrowsky Julia T, Leighton Tabitha, Cehovin Ana, Fay Petra C, Golding Josephine P, Maynard Emma, Alphey Luke, Rojas Alvarez Diana P, Coffey Lark L, Faria Nuno R, Maciel-de-Freitas Rafael, Maringer Kevin, Murray Kris A, Salje Henrik, Sang Rosemary, Vasconcelos Pedro F C, Leo Yee-Sin, Sinkins Steven P, de Vasconcelos Jocelyne Neto, Dadzie Samuel K, Harris Eva, Dos Santos Thais H, Velayudhan Raman, Wongsawat Jurai, Osterholm Michael T, Lackritz Eve M

机构信息

Center for Infectious Disease Research and Policy (CIDRAP), University of Minnesota, Minneapolis, Minnesota, USA.

Independent Consultant to CIDRAP, Wilmington, Delaware, USA.

出版信息

Open Forum Infect Dis. 2025 Jul 9;12(7):ofaf395. doi: 10.1093/ofid/ofaf395. eCollection 2025 Jul.

Abstract

The emergence and re-emergence of mosquito-borne arbovirus (MBV) diseases pose a rapidly expanding global health threat fueled by the convergence of multiple ecologic, economic, and social factors, including climate change, land use, poverty, deficiencies of water storage and sanitation, and limitations of vector control programs. On December 6, 2023, the Wellcome Trust and the University of Minnesota's Center for Infectious Disease Research and Policy held a meeting titled "An integrated approach to mosquito-borne arboviruses: a priority research agenda." The meeting comprised presentations, panels, and facilitated discussions aimed at describing the state of the field, highlighting recent accomplishments, identifying novel strategies, and defining priority research goals and approaches for addressing MBV disease preparedness and response. This report summarizes meeting discussions in 3 key areas: the changing epidemiology of MBV disease, current and potential transmission- and disease-monitoring strategies, and evolutionary impacts on disease burden and transmission. It concludes with a list of priority strategies for research and investment in MBV disease prevention, preparedness, and control. To prepare for future epidemics of MBV diseases, research and policy will benefit from a multipathogen approach to MBVs. Building on existing knowledge and systems, these efforts must address social and ecological factors and connect with other global health agendas.

摘要

蚊媒虫媒病毒(MBV)疾病的出现和再次出现构成了迅速扩大的全球健康威胁,多种生态、经济和社会因素的共同作用加剧了这一威胁,这些因素包括气候变化、土地利用、贫困、蓄水和卫生设施不足以及病媒控制项目的局限性。2023年12月6日,惠康基金会和明尼苏达大学传染病研究与政策中心召开了一次题为“蚊媒虫媒病毒的综合应对方法:优先研究议程”的会议。会议包括演讲、小组讨论和引导式讨论,旨在描述该领域的现状、突出近期成就、确定新策略,并明确应对MBV疾病防范和应对的优先研究目标及方法。本报告总结了会议在三个关键领域的讨论:MBV疾病不断变化的流行病学、当前及潜在的传播和疾病监测策略,以及对疾病负担和传播的进化影响。报告最后列出了在MBV疾病预防、防范和控制方面进行研究和投资的优先策略。为应对未来MBV疾病的流行,研究和政策将受益于针对MBV的多病原体方法。在现有知识和系统的基础上,这些努力必须解决社会和生态因素,并与其他全球健康议程相联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79da/12287632/0390d3e771eb/ofaf395f1.jpg

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