Xi Guangdi, Yang Fuguo, Xu Jianan, Liu Jingzhe, Chen Dexin
Qingdao University School of Nursing, Qingdao University, Qingdao, China.
Front Public Health. 2025 Jul 10;13:1562201. doi: 10.3389/fpubh.2025.1562201. eCollection 2025.
The objective of this review is to integrate the content and effectiveness of secondary prevention interventions in post-PCI patients so that provide direction for the selection of more effective secondary prevention measures in the future.
A narrative review was performed, which included a literature search without language and study design restrictions in PubMed, Embase, and MEDLINE from January 1, 2000, to May 15, 2023. Search terms included free-text words for the key concepts of "Percutaneous Coronary Intervention" "PCI" and "secondary prevention".
This study consolidated the measures of secondary prevention included in the studies and found that patient education strategies had the highest rate of use (78%), followed by exercise (56%), with smoking cessation, diet, blood pressure control, and medication also being used in the remainder. We critically analyzed these secondary prevention strategies and found that only 56% of these secondary preventions were effective in their use, with the remaining 44% having non-significant differences between the intervention and control groups. 44% of the studies incorporated mHealth, and mHealth had a facilitating effect on the intervention. We found that patients had better results on subjective measures after surgery ( < 0.05), while none of the objective measures were significant.
This study found that the use of secondary prevention in post-PCI patients is not limited to medication; five non-pharmacologic measures, namely patient education, exercise, dietary modification, blood pressure control, and smoking cessation, have also been actively used. Some studies have combined mHealth technology with secondary prevention measures with good results, in which the interactivity of mHealth should be focus on. However, changes in objective prognostic measures after the application of secondary prevention measures in post-PCI patients were not significant, indicating that the efficacy of the measures was not significant, which is an issue that deserves to be emphasized in subsequent studies. Meanwhile, educational, economic, and social support challenges in the older adult population may hinder the effective implementation of secondary prevention, future studies in the older adult population should prioritize addressing these issues to optimize the prognosis of older adult patients.
本综述的目的是整合PCI术后患者二级预防干预措施的内容和效果,以便为未来选择更有效的二级预防措施提供指导。
进行了一项叙述性综述,包括在2000年1月1日至2023年5月15日期间在PubMed、Embase和MEDLINE上进行无语言和研究设计限制的文献检索。检索词包括“经皮冠状动脉介入治疗”“PCI”和“二级预防”等关键概念的自由文本词。
本研究汇总了各项研究中包含的二级预防措施,发现患者教育策略的使用率最高(78%),其次是运动(56%),其余还包括戒烟、饮食、血压控制和药物治疗。我们对这些二级预防策略进行了批判性分析,发现这些二级预防措施中只有56%在使用中有效,其余44%在干预组和对照组之间无显著差异。44%的研究纳入了移动健康(mHealth),且移动健康对干预有促进作用。我们发现患者术后主观指标有更好的结果(P<0.05),而客观指标均无显著差异。
本研究发现,PCI术后患者二级预防的应用不仅限于药物治疗;患者教育、运动、饮食调整、血压控制和戒烟这五项非药物措施也得到了积极应用。一些研究将移动健康技术与二级预防措施相结合,取得了良好效果,其中应关注移动健康的交互性。然而,PCI术后患者应用二级预防措施后客观预后指标的变化并不显著,表明这些措施的疗效不显著,这是后续研究中值得强调的问题。同时,老年人群中的教育、经济和社会支持挑战可能会阻碍二级预防的有效实施,未来针对老年人群的研究应优先解决这些问题,以优化老年患者的预后。