Jörgensen T M, Stödkilde-Jörgensen H
Scand J Urol Nephrol. 1985;19(3):173-82. doi: 10.3109/00365598509180251.
The ureterovesical junction was bypassed on the left side with a tube in 9 pigs in order to study the dynamic alterations a vesico-ureteric reflux produces in a previously patent pyelo-ureter. Before bypassing, the median ureteric baseline activity was 1.6-2.0 A.P./min (action potentials/min). During bladder filling the median activity increased by 15-44% to 2.3 A.P./min, together with a slight increase in pelvic pressure. In the refluxing ureters the median baseline ureteric activity was 1.6 A.P./min. During bladder filling the pelvic pressure was the same as the bladder pressure and the median ureteric activity increased by 88% to 3.0 A.P./min. This increase in activity was seen as soon as the bladder filling started. The study adds information to suggest a neurogenic mediated reaction to sudden increases in bladder volume and pressure.
为了研究膀胱输尿管反流对先前通畅的肾盂输尿管产生的动态变化，对9只猪的左侧输尿管膀胱连接部进行了插管绕过。在绕过之前，输尿管中段的基线活动为1.6 - 2.0次动作电位/分钟（动作电位/分钟）。在膀胱充盈期间，中段活动增加了15 - 44%，达到2.3次动作电位/分钟，同时盆腔压力略有增加。在发生反流的输尿管中，输尿管中段的基线活动为1.6次动作电位/分钟。在膀胱充盈期间，盆腔压力与膀胱压力相同，输尿管中段活动增加了88%，达到3.0次动作电位/分钟。这种活动增加在膀胱充盈开始时就可见到。该研究补充了信息，提示对膀胱容量和压力突然增加存在神经源性介导的反应。
