Sahab Lujain, Newton Jonathon Timothy, Sabbah Wael
Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE5 9RS, UK.
Dent J (Basel). 2025 Jul 4;13(7):303. doi: 10.3390/dj13070303.
: The global rise in life expectancy and the resulting shift toward ageing populations pose significant public health and socioeconomic challenges. As healthy ageing becomes a priority, understanding the factors that support well-being in older age is essential. Oral health is increasingly recognised as a critical determinant of overall health and has been linked to chronic conditions. : To conduct a systematic review of longitudinal studies examining the relationship between oral health and healthy ageing. : Two independent reviewers conducted searches in three databases (MEDLINE, EMBASE, and LILACS) up to April 2025, following a defined search strategy. Grey literature was explored using Open Grey and Google Scholar. The quality and the risk of bias of the included studies were evaluated using the Newcastle Ottawa Quality Assessment Scale (NOS) for longitudinal studies. The review protocol was registered with the International Prospective Register of Systematic Reviews (CRD420251029090). : Four longitudinal studies reporting the association between oral health and healthy ageing were recognised and included. All selected studies were considered of good quality according to the NOS. The studies varied in defining and measuring healthy ageing, the follow-up period, the sample size, and the measure of oral health; therefore, it was not possible to perform a meta-analysis. The studies included in the review demonstrated a positive relationship between the number of natural teeth and healthy ageing. : Despite variations in the definition of healthy ageing and the application of different oral health indicators, the review identified significant associations between the number of natural teeth and trajectories of healthy ageing. : This review recognised significant longitudinal associations between oral health measures (number of teeth) and trajectories of healthy ageing. The findings emphasise the need to incorporate oral health into research and policy related to healthy ageing.
全球预期寿命的增长以及随之而来的人口老龄化趋势给公共卫生和社会经济带来了重大挑战。随着健康老龄化成为优先事项，了解支持老年人福祉的因素至关重要。口腔健康日益被视为整体健康的关键决定因素，并与慢性病相关联。
开展一项系统综述，以研究纵向研究中口腔健康与健康老龄化之间的关系。
两名独立评审员按照既定的检索策略，在截至2025年4月的三个数据库（MEDLINE、EMBASE和LILACS）中进行检索。利用Open Grey和谷歌学术搜索灰色文献。采用纽卡斯尔渥太华纵向研究质量评估量表（NOS）对纳入研究的质量和偏倚风险进行评估。该综述方案已在国际前瞻性系统综述注册库（CRD420251029090）注册。
识别并纳入了四项报告口腔健康与健康老龄化之间关联的纵向研究。根据NOS，所有选定研究均被认为质量良好。这些研究在健康老龄化的定义和测量、随访期、样本量以及口腔健康测量方面存在差异；因此，无法进行荟萃分析。综述中纳入的研究表明天然牙数量与健康老龄化之间存在正相关关系。
尽管健康老龄化的定义和不同口腔健康指标的应用存在差异，但该综述确定了天然牙数量与健康老龄化轨迹之间存在显著关联。
本综述确认了口腔健康指标（牙齿数量）与健康老龄化轨迹之间存在显著的纵向关联。研究结果强调有必要将口腔健康纳入与健康老龄化相关的研究和政策中。
