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磁性纳米颗粒的生物医学局限性以及趋磁细菌形式的生物相容性替代物

The Biomedical Limitations of Magnetic Nanoparticles and a Biocompatible Alternative in the Form of Magnetotactic Bacteria.

作者信息

Paul Natalia L, Carpa Rahela, Ionescu Rodica Elena, Popa Catalin Ovidiu

机构信息

Materials Science and Engineering Department, Faculty of Materials and Environmental Engineering, Technical University of Cluj-Napoca, 400641 Cluj-Napoca, Romania.

Light, Nanomaterials and Nanotechnology (L2N) Laboratory, CNRS EMR 7076, University of Technology of Troyes, 12 Rue Marie Curie, CS 42060, CEDEX, 10004 Troyes, France.

出版信息

J Funct Biomater. 2025 Jun 23;16(7):231. doi: 10.3390/jfb16070231.

DOI:10.3390/jfb16070231
PMID:40710446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12296043/
Abstract

Nanotechnology has an increasing impact and a great potential in various biological and medical applications. Magnetic nanoparticles (MNPs) stand out for their unique properties, a reason why they have a varied spectrum of applicability in different sectors of activity; in this paper we focus on the medical field. Magnetotactic bacteria (MTB) are a group of Gram-negative prokaryotes that migrate in one direction or another under the influence of an external magnetic field and are a category of microorganisms that constitutively perform the biomineralization of magnetic nanoparticles in the cytoplasm. This review focuses on the general and particular characteristics of magnetotactic bacteria in close correlation with their utility in the medical field, starting with the medical applications of magnetic nanoparticles and arriving at the potential role in nanomedicine of MNPs extracted from MTB.

摘要

纳米技术在各种生物和医学应用中产生着越来越大的影响，具有巨大的潜力。磁性纳米颗粒（MNPs）因其独特的性质而脱颖而出，这也是它们在不同活动领域具有广泛应用范围的原因；在本文中，我们将重点关注医学领域。趋磁细菌（MTB）是一类革兰氏阴性原核生物，它们在外部磁场的影响下向一个方向或另一个方向迁移，是一类在细胞质中组成性地进行磁性纳米颗粒生物矿化的微生物。本综述重点关注趋磁细菌的一般和特殊特征，以及它们与医学领域应用的紧密相关性，从磁性纳米颗粒的医学应用开始，到从趋磁细菌中提取的磁性纳米颗粒在纳米医学中的潜在作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853b/12296043/553637e437be/jfb-16-00231-g014.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853b/12296043/1b1b4c2fabb6/jfb-16-00231-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853b/12296043/675b8261761e/jfb-16-00231-g009.jpg
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