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巴雷特食管发生的癌。

Carcinoma arising in Barrett's esophagus.

作者信息

Sanfey H, Hamilton S R, Smith R R, Cameron J L

出版信息

Surg Gynecol Obstet. 1985 Dec;161(6):570-4.

PMID:4071370
Abstract

Between 1951 and 1983, 32 patients who had adenocarcinoma develop in Barrett's esophagus were identified at our institution. Twenty-nine patients were male (91 per cent) and 29 were white. Amongst the 23 patients in whom the relevant data were available, 78 per cent admitted to regular alcohol intake and 78 per cent smoked. Only one of these patients did not smoke or drink alcohol. Surprisingly, only 61 per cent of the patients had symptoms suggestive of gastroesophageal reflux and reflux was demonstrated roentgenographically in only 41 per cent. Twenty-one of the patients underwent esophagogastrectomy. Life table analysis revealed a survival rate of 34 per cent at two years and 14.8 per cent at five years.

摘要

1951年至1983年间,我院共确诊32例在巴雷特食管基础上发生腺癌的患者。其中29例为男性(占91%),均为白人。在有相关数据的23例患者中,78%的患者承认有规律饮酒,78%的患者吸烟。这些患者中只有1人既不吸烟也不饮酒。令人惊讶的是,只有61%的患者有胃食管反流的症状,而通过X线检查证实有反流的患者仅占41%。21例患者接受了食管胃切除术。生命表分析显示,两年生存率为34%,五年生存率为14.8%。

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引用本文的文献

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Clinical consequences of silent gastroesophageal reflux disease.无症状性胃食管反流病的临床后果
Curr Gastroenterol Rep. 2006 Jun;8(3):195-201. doi: 10.1007/s11894-006-0075-8.
2
Barrett's oesophagus: optimal strategies for prevention and treatment.巴雷特食管:预防与治疗的最佳策略
Drugs. 2003;63(6):555-64. doi: 10.2165/00003495-200363060-00003.
3
Short segments of Barrett's epithelium and intestinal metaplasia in normal appearing oesophagogastric junctions: the same or two different entities?外观正常的食管胃交界处的Barrett上皮和肠化生短节段:是同一实体还是两种不同实体?
Gut. 1998 May;42(5):659-62. doi: 10.1136/gut.42.5.659.
4
Cost effectiveness of detecting Barrett's cancer.检测巴雷特食管癌的成本效益
Gut. 1996 Oct;39(4):574-9. doi: 10.1136/gut.39.4.574.
5
Adenocarcinomas of esophagus and cardia in comparison with gastric carcinoma.食管和贲门腺癌与胃癌的比较。
J Cancer Res Clin Oncol. 1993;120(1-2):95-9. doi: 10.1007/BF01200731.
6
[Barrett esophagus as a precancerous condition].[巴雷特食管作为一种癌前病变]
Langenbecks Arch Chir. 1986;369:217-23. doi: 10.1007/BF01274357.
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Adenocarcinoma in Barrett's esophagus. A clinicopathologic study of 65 cases.巴雷特食管腺癌。65例临床病理研究。
Ann Surg. 1991 Feb;213(2):122-5. doi: 10.1097/00000658-199102000-00005.
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The neoplastic potential of columnar-lined (Barrett's) esophagus.柱状上皮化生(巴雷特)食管的肿瘤发生潜能。
World J Surg. 1992 Mar-Apr;16(2):308-12. doi: 10.1007/BF02071538.
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Outcome of surgical treatment of adenocarcinoma in Barrett's oesophagus.巴雷特食管腺癌的外科治疗结果
Gut. 1992 Nov;33(11):1454-8. doi: 10.1136/gut.33.11.1454.