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A novel polypeptide encoded by circSPIRE1 promotes prostate cancer proliferation and migration by restraining the ubiquitin-dependent degradation of LRP5.

作者信息

Hu Jintao, Shi Juanyi, Wang Junjie, Xiao Yunfei, Kong Degeng, Gao Mingchao, Luo Tianlong, Xu Shizhong, Yuan Zhihan, Ma Xinyi, Dong Xueseng, Huang Jingang, Liu Cheng, Xu Kewei

机构信息

Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, Guangdong, China.

Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, Guangdong, China.

出版信息

J Exp Clin Cancer Res. 2025 Jul 25;44(1):218. doi: 10.1186/s13046-025-03467-8.

DOI:10.1186/s13046-025-03467-8
PMID:40713830
Abstract
摘要

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本文引用的文献

1
CircRNA and lncRNA-encoded peptide in diseases, an update review.环状 RNA 和长链非编码 RNA 编码肽在疾病中的研究进展综述
Mol Cancer. 2024 Sep 30;23(1):214. doi: 10.1186/s12943-024-02131-7.
2
Molecular mechanisms of circular RNA translation.环状 RNA 翻译的分子机制。
Exp Mol Med. 2024 Jun;56(6):1272-1280. doi: 10.1038/s12276-024-01220-3. Epub 2024 Jun 14.
3
The Lancet Commission on prostate cancer: planning for the surge in cases.《柳叶刀》前列腺癌委员会:应对病例激增的规划
Lancet. 2024 Apr 27;403(10437):1683-1722. doi: 10.1016/S0140-6736(24)00651-2. Epub 2024 Apr 4.
4
Tumour circular RNAs elicit anti-tumour immunity by encoding cryptic peptides.肿瘤环状 RNA 通过编码隐藏肽引发抗肿瘤免疫。
Nature. 2024 Jan;625(7995):593-602. doi: 10.1038/s41586-023-06834-7. Epub 2023 Dec 13.
5
A positive feedback circuit driven by mA-modified circular RNA facilitates colorectal cancer liver metastasis.mA 修饰的环状 RNA 驱动的正反馈回路促进结直肠癌肝转移。
Mol Cancer. 2023 Dec 13;22(1):202. doi: 10.1186/s12943-023-01848-1.
6
Talazoparib plus enzalutamide in men with first-line metastatic castration-resistant prostate cancer (TALAPRO-2): a randomised, placebo-controlled, phase 3 trial.泰拉唑帕尼联合恩扎卢胺治疗一线转移性去势抵抗性前列腺癌(TALAPRO-2):一项随机、安慰剂对照、III 期临床试验。
Lancet. 2023 Jul 22;402(10398):291-303. doi: 10.1016/S0140-6736(23)01055-3. Epub 2023 Jun 4.
7
Circular MTHFD2L RNA-encoded CM-248aa inhibits gastric cancer progression by targeting the SET-PP2A interaction.环状 MTHFD2L RNA 编码的 CM-248aa 通过靶向 SET-PP2A 相互作用抑制胃癌进展。
Mol Ther. 2023 Jun 7;31(6):1739-1755. doi: 10.1016/j.ymthe.2023.04.013. Epub 2023 Apr 26.
8
A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR.环状 RNA ZKSCAN1 编码的一种新型多肽通过降解 mTOR 抑制 HCC。
Mol Cancer. 2023 Jan 23;22(1):16. doi: 10.1186/s12943-023-01719-9.
9
Pervasive translation of circular RNAs driven by short IRES-like elements.由短的 IRES 样元件驱动的环状 RNA 的普遍翻译。
Nat Commun. 2022 Jun 29;13(1):3751. doi: 10.1038/s41467-022-31327-y.
10
The functional roles of the circRNA/Wnt axis in cancer.环状 RNA/Wnt 轴在癌症中的功能作用。
Mol Cancer. 2022 May 5;21(1):108. doi: 10.1186/s12943-022-01582-0.