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一次急性呼吸道感染暴发的病毒和立克次氏体病因

Viral and rickettsial etiology of an outbreak of acute respiratory tract infection.

作者信息

Steiner N, Mihăilescu M, Petrescu A, Teodosiu O, Anghelescu S, Peiulescu P

出版信息

Virologie. 1985 Jul-Sep;36(3):195-200.

PMID:4071978
Abstract

An outbreak of 111 cases of acute respiratory tract infection was recorded in a community of the town "T" in April-May 1984. The clinical picture was severer than usual; 28% of the cases had to be hospitalized, average absenteeism being as high as 26 days per case. Serological investigations demonstrated the previous circulation of influenza virus B/Singapore/222/79 and the simultaneous circulation during the outbreak of influenza virus A/England/333/80 (H1N1) and of Rickettsia burneti (as also ascertained by isolation in the chick embryo of the former and by visualization by immunofluorescence in exfoliated cells of the latter pathogen). The association of the two etiological agents appears to account for the severe and protracted course of the disease.

摘要

1984年4月至5月期间,在“T”镇的一个社区记录了111例急性呼吸道感染病例的爆发。临床症状比往常更为严重;28%的病例需要住院治疗,平均缺勤天数高达每例26天。血清学调查显示,此前有乙型流感病毒新加坡/222/79的传播,在此次疫情爆发期间,甲型流感病毒英格兰/333/80(H1N1)和伯纳特立克次体同时传播(前者通过鸡胚分离确定,后者通过对脱落细胞进行免疫荧光观察确定)。两种病原体的联合感染似乎是导致该疾病病程严重且迁延的原因。

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