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附近卒中中心认证后黑人和白人患者的治疗结果。

Outcomes for Black and White Patients After Certification of Nearby Stroke Centers.

作者信息

Shen Yu-Chu, Kim Anthony S, Hsia Renee Y

机构信息

Department of Defense Management, Naval Postgraduate School, Monterey, California.

National Bureau of Economic Research, Cambridge, Massachusetts.

出版信息

JAMA Netw Open. 2025 Jul 1;8(7):e2522019. doi: 10.1001/jamanetworkopen.2025.22019.

Abstract

IMPORTANCE

It is unclear whether stroke center certification near a community is associated with similar benefits for Black and White patients.

OBJECTIVE

To assess changes in admission to stroke centers, receipt of acute stroke treatment, and health outcomes for Black compared with White patients after the certification of a new stroke center near their community.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study comprises Medicare fee-for-service patients from urban US communities with a primary diagnosis of acute ischemic stroke between January 1, 2009, and December 31, 2019, and compares changes in outcomes. Statistical analysis was performed from September 2024 to April 2025.

EXPOSURE

When a patient's community was exposed to the certification of a nearby stroke center relative to a patient of the same self-reported race in a community that was not exposed to a stroke center certification.

MAIN OUTCOMES AND MEASURES

A difference-in-differences framework was used to compare changes in (1) stroke center admission, (2) receipt of acute stroke treatments (thrombolytics and thrombectomy), and (3) health outcomes (home at 90 days and 1-year mortality) among Black and White patients. The empirical model was a linear probability model with community fixed effects.

RESULTS

This study included 2.1 million patients with stroke (15% Black patients and 85% White patients; 57% women; 15% aged 65-69 years, 16% aged 70-74 years, 18% aged 75-79 years, 19% aged 80-84 years, and 32% aged ≥85 years). After a newly certified stroke center opened near a community, the probability of admission to the stroke center increased for both White patients (15.6 percentage points [pp]; 95% CI, 14.6-16.6 pp) and Black patients (14.6 pp; 95% CI, 13.2-15.9 pp). Thrombolytic therapy increased for White patients by 0.2 pp (95% CI, 0.0-0.4 pp) but decreased for Black patients by 0.4 pp (95% CI, -0.7 to -0.1 pp) compared with their control communities. Black patients also had a 0.5-pp decrease in thrombectomy (95% CI, -0.6 to -0.3 pp). One-year mortality remained stable for White patients, while mortality for Black patients increased by 0.5 pp (95% CI, 0.1-0.9 pp).

CONCLUSIONS AND RELEVANCE

This cohort study of 2.1 million patients with stroke found that stroke center certification near a community was associated with similar increases in rates of admission to the stroke center for Black and White patients, but it was associated with increased rates of receiving thrombolytics only for White patients. Thrombolysis and thrombectomy rates did not increase for Black patients who were exposed to a newly certified stroke center nearby. This study suggests that, despite the expansion of certified stroke centers, disparities in stroke care between Black and White patients persist.

摘要

重要性

尚不清楚社区附近的卒中中心认证对黑人和白人患者是否具有相似的益处。

目的

评估新的卒中中心在社区附近认证后,与白人患者相比,黑人患者在卒中中心入院、接受急性卒中治疗以及健康结局方面的变化。

设计、设置和参与者:这项队列研究纳入了2009年1月1日至2019年12月31日期间美国城市社区中主要诊断为急性缺血性卒中的医疗保险按服务收费患者,并比较结局变化。统计分析于2024年9月至2025年4月进行。

暴露因素

当患者所在社区相对于未暴露于卒中中心认证的社区中具有相同自我报告种族的患者,暴露于附近卒中中心的认证时。

主要结局和测量指标

采用差异中的差异框架,比较黑人和白人患者在以下方面的变化:(1)卒中中心入院情况;(2)接受急性卒中治疗(溶栓和取栓)的情况;(3)健康结局(90天时在家以及1年死亡率)。实证模型为具有社区固定效应的线性概率模型。

结果

本研究纳入了210万例卒中患者(15%为黑人患者,85%为白人患者;57%为女性;15%年龄在65 - 69岁,16%年龄在70 - 74岁,18%年龄在75 - 79岁,19%年龄在80 - 84岁,32%年龄≥85岁)。在社区附近新认证的卒中中心开业后,白人患者(15.6个百分点[pp];95%置信区间[CI],14.6 - 16.6 pp)和黑人患者(14.6 pp;95% CI,13.2 - 15.9 pp)进入卒中中心的概率均增加。与对照社区相比,白人患者的溶栓治疗增加了0.2 pp(95% CI,0.0 - 0.4 pp),而黑人患者则减少了0.4 pp(95% CI, - 0.7至 - 0.1 pp)。黑人患者的取栓治疗也减少了0.5 pp(95% CI, - 0.6至 - 0.3 pp)。白人患者的1年死亡率保持稳定,而黑人患者的死亡率增加了0.5 pp(95% CI,0.1 - 0.9 pp)。

结论及相关性

这项对210万例卒中患者的队列研究发现,社区附近的卒中中心认证与黑人和白人患者进入卒中中心的比例相似增加相关,但仅与白人患者接受溶栓治疗的比例增加相关。暴露于附近新认证卒中中心的黑人患者的溶栓和取栓率并未增加。这项研究表明,尽管认证卒中中心有所增加,但黑人和白人患者在卒中治疗方面的差异仍然存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7839/12305387/91825398942c/jamanetwopen-e2522019-g001.jpg

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