Li Caitlin Naureckas, Blumenthal Jennifer A, Sick-Samuels Anna C
Division of Infectious Diseases, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.
J Pediatric Infect Dis Soc. 2025 Jul 26. doi: 10.1093/jpids/piaf065.
Untargeted molecular tests are increasingly available for diagnosis of infectious diseases. In this national survey, plasma metagenomic next-generation sequencing had widespread use (89.8%), but disparate frequency from a few times ever (18.4%) to > weekly (9.6%). Respondents offered thoughtful insights into stewardship and future research needs.
非靶向分子检测在传染病诊断中越来越普及。在这项全国性调查中,血浆宏基因组下一代测序得到广泛应用(89.8%),但使用频率差异很大,从偶尔几次(18.4%)到每周多次(9.6%)不等。受访者对管理和未来研究需求提出了深刻见解。