Wu Hung-Chieh, Chen Fu-Lun, Chiang Yuan-Ching, Lo Yi-June, Lin Chun-Li, Chang Wei-Jen, Huang Haw-Ming
School of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.
Division of Infectious Diseases, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.
Bioengineering (Basel). 2025 Jun 20;12(7):680. doi: 10.3390/bioengineering12070680.
Breath-actuated nebulizers used in aerosol therapy are vital to children and patients with disabilities and stand out for their ability to accurat ely deliver medication while minimizing waste. Their performance can be measured according to the mass output and droplet size. This study aimed to analyze how the baffle impact surface geometries affect the pressure and flow streamlines inside the nebulizer using computational fluid dynamics (CFD). Computer-aided design models of conical symmetric, conical asymmetric, and arc-shaped baffle designs were analyzed using CFD simulations, with the optimal spray output validated through the differences in mass. Conical baffles exhibited superior pressure distribution and output streamlines at 0.25 cm protrusion, suggesting that the nebulizer spray performance can be enhanced by using such a conical baffle impact surface. This result serves as a valuable reference for future research.
雾化治疗中使用的呼吸驱动雾化器对儿童和残疾患者至关重要,其能够在减少浪费的同时准确给药的能力尤为突出。其性能可根据质量输出和液滴大小来衡量。本研究旨在使用计算流体动力学(CFD)分析挡板冲击表面几何形状如何影响雾化器内部的压力和流动流线。使用CFD模拟分析了圆锥形对称、圆锥形不对称和弧形挡板设计的计算机辅助设计模型,并通过质量差异验证了最佳喷雾输出。圆锥形挡板在0.25厘米突出时表现出优越 的压力分布和输出流线,这表明使用这种圆锥形挡板冲击表面可提高雾化器的喷雾性能。该结果为未来的研究提供了有价值的参考。