Tomičić Zorica, Šarić Ljubiša, Tomičić Ružica
Institute of Food Technology in Novi Sad, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.
Faculty of Technology, University of Novi Sad, Bulevar cara Lazara 1, 21000 Novi Sad, Serbia.
Antibiotics (Basel). 2025 Jul 3;14(7):674. doi: 10.3390/antibiotics14070674.
Postbiotics are defined as non-viable metabolites or compounds produced by probiotic microorganisms with significant impact on human health. The growing interest in postbiotics is supported by numerous studies due to their additional benefits over probiotics that show positive outcomes for specific conditions, as well as their application as biopreservatives in the food industry. Their potential in functional foods and therapeutic applications is increasingly recognized as they exhibit stability, safety, and diverse biological activities. As for their most important biological roles, postbiotics have been shown to have effective anti-inflammatory, antimicrobial, antioxidant, and anticancer properties, in addition to reducing food allergies. The application of postbiotics in functional foods contributes to improving intestinal health and reducing the risk of foodborne diseases. The concept of postbiotics is relatively new in the food industry. They offer a promising alternative to conventional food preservatives due to their ability to inhibit pathogenic bacteria and extend shelf life. Considering the diversity of postbiotic compounds and their significant biological activities, this review presents and discusses the mechanisms of action and future trends in their application in the food industry and their impact on human health. Increasing research and development in the production and formulation of postbiotics will play a key role in the upward trajectory of the market.
后生元被定义为益生菌微生物产生的对人类健康有重大影响的非活性代谢产物或化合物。由于后生元相对于益生菌具有额外的益处,在特定情况下显示出积极效果,以及它们在食品工业中作为生物防腐剂的应用,众多研究支持了对后生元日益增长的兴趣。随着它们表现出稳定性、安全性和多样的生物活性,它们在功能性食品和治疗应用中的潜力越来越受到认可。至于它们最重要的生物学作用,后生元除了能减少食物过敏外,还被证明具有有效的抗炎、抗菌、抗氧化和抗癌特性。后生元在功能性食品中的应用有助于改善肠道健康并降低食源性疾病的风险。后生元的概念在食品工业中相对较新。由于它们能够抑制病原菌并延长保质期,它们为传统食品防腐剂提供了一个有前景的替代方案。考虑到后生元化合物的多样性及其显著的生物活性,本综述介绍并讨论了它们在食品工业中的作用机制、未来应用趋势以及对人类健康的影响。后生元生产和配方方面不断增加的研发将在市场的上升趋势中发挥关键作用。