[向大鼠海马体注射卡巴胆碱后解离状态的发展]
[Development of a dissociated state in the rat after administration of carbacholine into the hippocampus].
作者信息
Arkhipov V I, Azarashvili A A
出版信息
Zh Vyssh Nerv Deiat Im I P Pavlova. 1985 Sep-Oct;35(5):920-5.
PMID:4072408
Abstract
Food-procuring conditioned reaction was elaborated in rats. A single injection of carbacholine into the dorsal area of the hippocampus elicited prolonged (for several days) stable amnesia, during which elaboration of a second habit in the same animals proved possible. After cessation of the agent action, the initially elaborated conditioned reaction recurred. The obtained results allow to interpret the amnesia elicited by injection of carbacholine into the hippocampus as a dissociated state.
摘要
在大鼠身上建立了获取食物的条件反应。向海马体背侧区域单次注射卡巴胆碱会引发长时间（持续数天）的稳定失忆，在此期间，同一动物建立第二种习惯是可能的。在药物作用停止后，最初建立的条件反应会再次出现。所获得的结果使我们能够将向海马体注射卡巴胆碱引发的失忆解释为一种分离状态。
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