Arkhipov V I, Arkhipova G V, Fedotova I B
Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 Nov-Dec;40(6):1140-4.
Dependence was studied of pentobarbital effects at dissociated learning in rats of KM line after intraperitoneal injection of antioxidant phenozan-K. It was shown that preliminary (before 1.5 hour) injection of 40 mg/kg of phenozan-K to animals changed the composition (index of oxidation S) of cells lipids of rats brain membranes and simultaneously increased the sensitivity to pentobarbital. Injection of half a dose of pentobarbital, which caused dissociated state, against the background of antioxidant action had the same effect as the full dose (15 mg/kg).
研究了在向KM系大鼠腹腔注射抗氧化剂酚嗪-K后，戊巴比妥对其分离学习的影响。结果表明，在给药前1.5小时向动物注射40mg/kg的酚嗪-K，可改变大鼠脑膜细胞脂质的组成（氧化指数S），同时增加对戊巴比妥的敏感性。在抗氧化作用的背景下，注射半剂量戊巴比妥（可引起分离状态）产生的效果与全剂量（15mg/kg）相同。
