Marschalek Marie-Louise, Marculescu Rodrig, Schneeberger Christian, Marschalek Julian, Hager Marlene, Krysiak Robert, Ott Johannes
Department of Obstetrics and Gynecology, Clinical Division of Gynecologic Endocrinology and Reproductive Medicine of the Medical University Vienna, 1090 Vienna, Austria.
Department of Laboratory Medicine, Institute of Immunology, Medical University Vienna, 1090 Vienna, Austria.
J Clin Med. 2025 Jul 18;14(14):5103. doi: 10.3390/jcm14145103.
: Polycystic ovary syndrome (PCOS) is associated with an elevated risk of impaired mental health and psychiatric disorders, such as depression and anxiety. Physical factors like weight and hirsutism, as well as psychological factors, such as self-esteem and coping strategies, are all known to have an influence on mental health status. To assess psychological symptoms in women with and without PCOS, by use of the well-established, validated self-report questionnaire: Symptom Checklist-90-Revised (SCL-90); to determine the reliability of the SCL-90 for assessment of PCOS patients. : Prospective case-control study. : Psychological symptoms were assessed using the German version of the SCL-90 in 31 PCOS women and 31 healthy controls. To test the impact of various parameters on numerical outcome parameters, correlation analyses were conducted. : PCOS women revealed significantly increased SCL-90 scores in seven out of the nine subscales (hostility subscale, anxiety subscale, depression subscale, paranoid ideation subscale, psychoticism subscale, somatization subscale, interpersonal sensitivity subscale, obsessive compulsive subscale), as well as in all three global indices ( < 0.05). SCL-90 scores were significantly positively correlated with perceived total stress and perceived helplessness and significantly negatively correlated with perceived self-efficacy ( < 0.05). : PCOS women experienced higher levels of psychological symptoms including depressive and anxiety symptoms. Higher perceived stress, higher perceived helplessness and lower self-efficacy were associated with more psychological symptoms. Hence, there is a need to support PCOS women with their emotional regulation and coping strategies.
多囊卵巢综合征（PCOS）与心理健康受损及精神障碍风险升高有关，如抑郁和焦虑。体重和多毛等身体因素以及自尊和应对策略等心理因素，均已知会对心理健康状况产生影响。通过使用成熟且经过验证的自我报告问卷：症状自评量表90修订版（SCL - 90），来评估患有和未患有PCOS的女性的心理症状；确定SCL - 90评估PCOS患者的可靠性。：前瞻性病例对照研究。：使用SCL - 90德语版对31名PCOS女性和31名健康对照者进行心理症状评估。为了测试各种参数对数值结果参数的影响，进行了相关性分析。：PCOS女性在九个分量表中的七个（敌对分量表、焦虑分量表、抑郁分量表、偏执观念分量表、精神病性分量表、躯体化分量表、人际敏感分量表、强迫观念及行为分量表）以及所有三个总体指标上的SCL - 90得分均显著升高（<0.05）。SCL - 90得分与感知到的总压力和感知到的无助感显著正相关，与感知到的自我效能感显著负相关（<0.05）。：PCOS女性经历了更高水平的心理症状，包括抑郁和焦虑症状。更高的感知压力、更高的感知无助感和更低的自我效能感与更多的心理症状相关。因此，有必要在情绪调节和应对策略方面支持PCOS女性。
