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系统性硬化症的心理特征:一项观察性研究的结果

Psychological features of systemic sclerosis: results from an observational study.

作者信息

Romanazzo Sara, Rometsch Caroline, Marangoni Alessia, Guiducci Serena, Cosci Fiammetta

机构信息

Department of Health Sciences, University of Florence, Florence, Italy.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

出版信息

Front Med (Lausanne). 2024 Dec 6;11:1473587. doi: 10.3389/fmed.2024.1473587. eCollection 2024.

DOI:10.3389/fmed.2024.1473587
PMID:39712185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11658978/
Abstract

OBJECTIVES

(a) Assessing mental disorders, psychological distress, psychological wellbeing in patients with systemic sclerosis (SSc); (b) identifying psychological features independently contributing to the status of having the diagnosis of SSc.

METHODS

Two hundred SSc outpatients were compared with 100 healthy subjects. Mental disorders were assessed via the Mini International Neuropsychiatric Interview (MINI). Self-reported rating scales were administered: Health Assessment Questionnaire Disability Index (HAQ-DI), Symptom Checklist-90-Revised (SCL-90-R), Psychological Well Being scales (PWB). General linear models allowed to verify which psychological feature would individually make unique contributions to overall status of having the diagnosis of SSc.

RESULTS

Major depressive episode/disorder, panic disorder were more prevalent among patients with SSc ( < 0.05); SCL-90-R somatization and depression were more severe ( < 0.05) in SSc; PWB personal growth, positive relationships with others, purposes in life were poorer ( < 0.05) in patients with SSc if compared to healthy controls. The final general linear model, accounting for 20.4% of variance, showed that having the diagnosis of SSc was associated to lower SCL-90-R paranoid ideation and poorer PWB relationships with others.

CONCLUSION

SSc showed to present psychological features in need of assessment since some of them individually made unique contributions to overall status of having the SSc diagnosis.

摘要

目的

(a)评估系统性硬化症(SSc)患者的精神障碍、心理困扰和心理健康状况;(b)确定独立影响SSc诊断状态的心理特征。

方法

将200名SSc门诊患者与100名健康受试者进行比较。通过迷你国际神经精神访谈(MINI)评估精神障碍。使用自我报告评定量表:健康评估问卷残疾指数(HAQ-DI)、症状自评量表90修订版(SCL-90-R)、心理健康量表(PWB)。采用一般线性模型来验证哪些心理特征会分别对SSc诊断的总体状态产生独特影响。

结果

重度抑郁发作/障碍、惊恐障碍在SSc患者中更为普遍(<0.05);SSc患者的SCL-90-R躯体化和抑郁症状更严重(<0.05);与健康对照组相比,SSc患者的PWB个人成长、与他人的积极关系、生活目标较差(<0.05)。最终的一般线性模型解释了20.4%的方差,结果显示,SSc诊断与较低的SCL-90-R偏执观念以及较差的PWB与他人关系相关。

结论

SSc显示出需要评估的心理特征,因为其中一些特征分别对SSc诊断的总体状态产生了独特影响。

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