Hu Jingyi, Wang Longfei, Zhou Meng, Dongzhou Moyan, Wang Yiran, Xiao Menglan, Zhao Mingqin, Lai Miao
Flavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450002, China.
Food Chem X. 2025 Jul 17;29:102797. doi: 10.1016/j.fochx.2025.102797. eCollection 2025 Jul.
Heterocyclic aroma compounds are a type of edible fragrances with strong nutty and baking aromas, which can improve food flavor. However, their applications are limited due to high volatility and poor stability. Therefore, the development of effective controlled release technologies is required. In this study, five characteristic heterocyclic aroma compounds 2,3-diethyl-5-methylpyrazine (DEMP), 3-ethylpyridine (ELPD), 3-acetylpyridine (ATPD), 5-methylfurfural (MTFF), and furfuryl alcohol (FFAH) were utilized as core materials, and β-cyclodextrin (β-CD)/chitosan (CS) were used as composite wall materials to prepare thermal stabilized microcapsules, with an encapsulation efficiency of 77.43 %-83.32 %. Microcapsules demonstrated superior thermal and storage stability. Furthermore, molecular dynamics (MD) simulations revealed that the primary interactions between the host and guest molecules were van der Waals forces. FFAH/β-CD + CS could form hydrogen bonds more readily. The MM-PBSA result indicated that FFAH/β-CD + CS and ATPD/β-CD + CS microcapsules exhibited greater stability. This research expands the potential applications of heterocyclic aroma compounds in the food industry.
杂环香气化合物是一类具有浓郁坚果和烘焙香气的食用香料，能够改善食品风味。然而，由于其高挥发性和稳定性差，它们的应用受到限制。因此，需要开发有效的控释技术。在本研究中，以五种特征性杂环香气化合物2,3-二乙基-5-甲基吡嗪（DEMP）、3-乙基吡啶（ELPD）、3-乙酰基吡啶（ATPD）、5-甲基糠醛（MTFF）和糠醇（FFAH）为芯材，以β-环糊精（β-CD）/壳聚糖（CS）为复合壁材制备热稳定微胶囊，包封率为77.43%-83.32%。微胶囊表现出优异的热稳定性和储存稳定性。此外，分子动力学（MD）模拟表明，主体分子与客体分子之间的主要相互作用是范德华力。FFAH/β-CD + CS更容易形成氢键。MM-PBSA结果表明，FFAH/β-CD + CS和ATPD/β-CD + CS微胶囊表现出更高的稳定性。本研究拓展了杂环香气化合物在食品工业中的潜在应用。
