Department of Chemical and Biomolecular Engineering, National University of Singapore, 119077, Singapore.
College of Food Science, Shenyang Agricultural University, Shenyang 110866, China.
Int J Biol Macromol. 2023 Jul 1;242(Pt 1):124784. doi: 10.1016/j.ijbiomac.2023.124784. Epub 2023 May 10.
Probiotics provide several benefits for humans, including restoring the balance of gut bacteria, boosting the immune system, and aiding in the management of certain conditions such as irritable bowel syndrome and lactose intolerance. However, the viability of probiotics may undergo a significant reduction during food storage and gastrointestinal transit, potentially hindering the realization of their health benefits. Microencapsulation techniques have been recognized as an effective way to improve the stability of probiotics during processing and storage and allow for their localization and slow release in intestine. Although, numerous techniques have been employed for the encapsulation of probiotics, the encapsulation techniques itself and carrier types are the main factors affecting the encapsulate effect. This work summarizes the applications of commonly used polysaccharides (alginate, starch, and chitosan), proteins (whey protein isolate, soy protein isolate, and zein) and its complex as the probiotics encapsulation materials; evaluates the evolutions in microencapsulation technologies and coating materials for probiotics, discusses their benefits and limitations, and provides directions for future research to improve targeted release of beneficial additives as well as microencapsulation techniques. This study provides a comprehensive reference for current knowledge pertaining to microencapsulation in probiotics processing and suggestions for best practices gleaned from the literature.
益生菌为人类提供了多种益处,包括恢复肠道细菌平衡、增强免疫系统,以及帮助管理某些疾病,如肠易激综合征和乳糖不耐受。然而,益生菌在食品储存和胃肠道转运过程中的存活率可能会显著降低,从而可能阻碍其健康益处的实现。微胶囊化技术已被认为是在加工和储存过程中提高益生菌稳定性的有效方法,并允许其在肠道中定位和缓慢释放。尽管已经采用了许多技术来封装益生菌,但封装技术本身和载体类型是影响封装效果的主要因素。本工作总结了常用多糖(海藻酸钠、淀粉和壳聚糖)、蛋白质(乳清蛋白分离物、大豆蛋白分离物和玉米醇溶蛋白)及其复合物作为益生菌包埋材料的应用;评估了益生菌微胶囊化技术和包衣材料的最新进展,讨论了它们的优缺点,并为未来的研究提供了方向,以改善有益添加剂的靶向释放和微胶囊化技术。本研究为益生菌加工中微胶囊化的现有知识提供了全面的参考,并从文献中提出了最佳实践建议。
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