Heiskanen O, Lehtosalo J
Acta Neurochir (Wien). 1985;78(1-2):1-3. doi: 10.1007/BF01809233.
A report is given on 118 children operated on for cerebellar astrocytoma, ependymoma or medulloblastoma in 1968-1982. During the first period (1968-1975) when the diagnosis was based on ventriculography and the operation performed later on the same day, the surgical mortality was 5%, 22%, and 16% respectively in these tumours. In the period since 1976, during which the diagnosis was based on CT and preoperative shunting was routine with the posterior fossa operation performed a week later and an operation microscope was available, no surgical mortality occurred. In patients with ependymoma or medulloblastoma the shunt was left in permanently; in patients with astrocytoma the shunt was removed if the patient tolerated its closure. The prognosis for astrocytoma was excellent. The 10-year survival rate was 97%. The five-year survival rate for medulloblastoma was 27% and the 10-year survival rate 13% which are less than the rates generally reported. For ependymoma patients the prognosis was poor whatever the therapy.
本文报告了1968年至1982年间接受小脑星形细胞瘤、室管膜瘤或髓母细胞瘤手术的118例儿童病例。在第一阶段（1968 - 1975年），诊断基于脑室造影，且在同一天晚些时候进行手术，这些肿瘤的手术死亡率分别为5%、22%和16%。自1976年起，诊断基于CT，术前常规进行分流术，一周后进行后颅窝手术且可使用手术显微镜，在此期间未发生手术死亡。对于室管膜瘤或髓母细胞瘤患者，分流管永久留置；对于星形细胞瘤患者，如果患者能耐受封堵分流管，则将其移除。星形细胞瘤的预后极佳，10年生存率为97%。髓母细胞瘤的5年生存率为27%，10年生存率为13%，低于一般报道的数据。对于室管膜瘤患者，无论采用何种治疗方法，预后都很差。
