Grove G L
Am J Ind Med. 1985;8(4-5):483-9. doi: 10.1002/ajim.4700080430.
Techniques have been developed for studying age-associated changes in human skin, including its vulnerability to external insults and its capacity for healing. Possible application of these methods for studying the effects of repeated mechanical trauma to the skin of workers is discussed. The methods include procedures for inflicting standardized superficial wounds and nonintrusive techniques for measuring damage, rate of skin repair via measurement of transepidermal water loss, and characterization of altered surface features using image analyses. These approaches have the great advantage of allowing quantification.
已经开发出了用于研究人类皮肤与年龄相关变化的技术,包括其对外界损伤的易感性及其愈合能力。本文讨论了这些方法在研究反复机械性创伤对工人皮肤影响方面的可能应用。这些方法包括造成标准化浅表伤口的程序,以及通过测量经表皮水分流失来测量损伤、皮肤修复率的非侵入性技术,和使用图像分析来表征表面特征变化的技术。这些方法具有能够进行量化的巨大优势。