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埃塞俄比亚西部阿尔西地区部分公立医院胃肠病学和肝病科门诊中成年患者(≥18岁)慢性肝病的严重程度及相关因素:一项横断面研究

Magnitude and factors associated with chronic liver disease among adults (≥ 18 Years) attending gastroenterology and hepatology clinics in selected public hospitals, West Arsi Zone, Ethiopia: a cross-sectional study.

作者信息

Gage Beresa Lema, Gela Debela, Wurjine Teshome Habte, Habte Teshome

机构信息

Shashamane Campus School of Nursing and Midwifery's Department of Nursing, Madda Walabu University, Shashamane, Oromia, Ethiopia.

School of Nursing and Midwifery's Department of Nursing, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

BMC Public Health. 2025 Jul 29;25(1):2575. doi: 10.1186/s12889-025-23811-z.

Abstract

BACKGROUND

Chronic liver disease (CLD) is a growing global public health issue and ranks as the seventh leading cause of death in Ethiopia. However, regional-level data particularly from the West Arsi Zone are scarce. This study aimed to fill this gap by assessing the burden and key determinants of CLD among adults attending liver clinics, providing essential evidence for targeted interventions.

OBJECTIVE

To determine the magnitude and associated factors with medically confirmed CLD among adult patients (≥ 18 years) undergoing follow-up for suspected or confirmed CLD in three public hospitals in the West Arsi Zone.

METHODOLOGY

An institution-based cross-sectional study was conducted from February to July 2022. A total of 384 adult participants were selected using systematic random sampling. Data were collected through structured interviews and medical record reviews. Multivariable binary logistic regression was used to identify factors associated with CLD, with adjusted odds ratios (AOR) and 95% confidence intervals (CI) reported.

RESULTS

All 384 selected participants completed the study, yielding a response rate of 100%. Among them, 60.2% (231/384) were clinically diagnosed with chronic liver disease (CLD), with a higher prevalence observed among males (62%).

摘要

背景

慢性肝病(CLD)是一个日益严重的全球公共卫生问题,在埃塞俄比亚是第七大死因。然而,特别是来自西阿尔西地区的区域层面数据稀缺。本研究旨在通过评估肝病门诊成年患者中慢性肝病的负担和关键决定因素来填补这一空白,为有针对性的干预措施提供重要证据。

目的

确定在西阿尔西地区三家公立医院接受疑似或确诊慢性肝病随访的成年患者(≥18岁)中经医学确认的慢性肝病的严重程度及相关因素。

方法

于2022年2月至7月开展了一项基于机构的横断面研究。采用系统随机抽样法共选取了384名成年参与者。通过结构化访谈和病历审查收集数据。使用多变量二元逻辑回归来确定与慢性肝病相关的因素,并报告调整后的优势比(AOR)和95%置信区间(CI)。

结果

所有384名选定的参与者均完成了研究,应答率为100%。其中,60.2%(231/384)临床诊断为慢性肝病(CLD),男性患病率更高(62%)。

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