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西班牙卡斯蒂利亚-莱昂地区水源中潜在致病性自由生活阿米巴的高度多样性和流行率。

High Diversity and Prevalence of Potentially Pathogenic Free-Living Amoebae in Water Sources from Castilla y León, Spain.

作者信息

Pérez-Pérez Patricia, Rodríguez-Escolar Iván, Piñero José E, Morchón Rodrigo, Lorenzo-Morales Jacob

机构信息

Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna (ULL), 38206 San Cristóbal de La Laguna, Spain.

Departamento de Obstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Spain.

出版信息

Pathogens. 2025 Jun 25;14(7):637. doi: 10.3390/pathogens14070637.

DOI:10.3390/pathogens14070637
PMID:40732685
Abstract

Free-living amoebae (FLA) such as spp., , , , and spp. are causal agents of deadly and/or disabling infections in humans. Despite recent data showing an increase in infection cases worldwide, studies on the prevalence of these emerging pathogens in water sources are scarce. Moreover, climate change is believed to facilitate the expansion and persistence of these environmental pathogens, further emphasizing the need for comprehensive surveillance. Therefore, the current study investigates the variety and abundance of free-living amoebae in different water sources in the autonomous community of Castilla y León, Spain, during different seasons of the year. was the most prevalent species and was detected in rivers, swamps, irrigation waters, swimming pools and recreational fountains. Moreover, genera such as and and were also identified. This study highlights the diversity of FLA in the region and their relationship with local water characteristics. Given that certain FLA species are opportunistic pathogens, these results emphasize the necessity of monitoring this area and water sources.

摘要

自由生活阿米巴(FLA),如 属、 属、 属、 属、 属和 属,是人类致命和/或致残感染的病原体。尽管最近的数据显示全球感染病例有所增加,但关于这些新兴病原体在水源中流行情况的研究却很少。此外,气候变化被认为会促进这些环境病原体的扩散和持续存在,这进一步凸显了进行全面监测的必要性。因此,本研究调查了西班牙卡斯蒂利亚-莱昂自治区不同季节不同水源中自由生活阿米巴的种类和丰度。 是最常见的物种,在河流、沼泽、灌溉用水、游泳池和休闲喷泉中均有检测到。此外,还鉴定出了 属、 属和 属等属。本研究突出了该地区自由生活阿米巴的多样性及其与当地水特征的关系。鉴于某些自由生活阿米巴物种是机会性病原体,这些结果强调了监测该地区和水源的必要性。

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本文引用的文献

1
Isolation and Molecular Identification of Pathogenic Free-Living Amoebae from Environmental Samples in Tenerife, Canary Islands, Spain.从西班牙加那利群岛特内里费岛的环境样本中分离和分子鉴定致病性自由生活阿米巴
ACS ES T Water. 2025 May 2;5(6):2861-2869. doi: 10.1021/acsestwater.4c00573. eCollection 2025 Jun 13.
2
Multiplex Real-Time Polymerase Chain Reaction Assay To Detect Acanthamoeba spp., Vermamoeba vermiformis, Naegleria fowleri, and Balamuthia mandrillaris in Different Water Sources.多重实时聚合酶链反应检测法检测不同水源中的棘阿米巴属、变形虫、福氏耐格里阿米巴和曼氏利什曼原虫。
Am J Trop Med Hyg. 2024 Aug 6;111(4):785-790. doi: 10.4269/ajtmh.24-0028. Print 2024 Oct 2.
3
Spatiotemporal distribution of thermophilic free-living amoebae in recreational waters: A 5-year survey in Guadeloupe (French West Indies).
温生自由生活阿米巴在娱乐水中的时空分布:法属西印度群岛瓜德罗普的 5 年调查。
Sci Total Environ. 2024 Sep 1;941:173318. doi: 10.1016/j.scitotenv.2024.173318. Epub 2024 May 20.
4
Diagnostic Considerations for Non- Amoebic Keratitis and Clinical Outcomes.非阿米巴性角膜炎的诊断考量及临床结果
Pathogens. 2022 Feb 8;11(2):219. doi: 10.3390/pathogens11020219.
5
The increasing importance of Vermamoeba vermiformis.棘阿米巴原虫的重要性日益增加。
J Eukaryot Microbiol. 2021 Sep;68(5):e12857. doi: 10.1111/jeu.12857. Epub 2021 Jun 30.
6
Free living amoebae isolation in irrigation waters and soils of an insular arid agroecosystem.在一个岛屿干旱农业生态系统的灌溉水中和土壤中分离自由生活的阿米巴虫。
Sci Total Environ. 2021 Jan 20;753:141833. doi: 10.1016/j.scitotenv.2020.141833. Epub 2020 Aug 22.
7
Pathogenic free-living amoebic encephalitis in Japan.日本的自由生活阿米巴性脑炎。
Neuropathology. 2019 Aug;39(4):251-258. doi: 10.1111/neup.12582. Epub 2019 Jun 26.
8
Free-living amoebae and squatters in the wild: ecological and molecular features.自由生活的阿米巴虫和野外的寄居者:生态和分子特征。
FEMS Microbiol Rev. 2019 Jul 1;43(4):415-434. doi: 10.1093/femsre/fuz011.
9
Vermamoeba vermiformis as etiological agent of a painful ulcer close to the eye.微小内蜒阿米巴作为眼部附近疼痛性溃疡的病原体。
Parasitol Res. 2019 Jun;118(6):1999-2004. doi: 10.1007/s00436-019-06312-y. Epub 2019 Apr 10.
10
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