Krishnan Mohan Raj, Alshabib Reem M, Alsharaeh Edreese H
College of Science and General Studies, Alfaisal University, P.O. Box 50927, Riyadh 11533, Saudi Arabia.
Polymers (Basel). 2025 Jul 18;17(14):1970. doi: 10.3390/polym17141970.
This study reports the impact of a silver nanoparticles/reduced graphene oxide@titanium dioxide nanocomposite (Ag/rGO@TiO) on the mechanical and biocompatibility properties of poly(styrene-co-methylmethacrylate)/poly methyl methacrylate (PS-PMMA/PMMA)-based bone cement. The chemical, structural, mechanical, and thermal characteristics of Ag/rGO@TiO nanocomposite-reinforced PS-PMMA bone cement ((Ag/rGO@TiO)/(PS-PMMA)/PMMA) were evaluated using Fourier Transform Infrared spectroscopy (FT-IR), X-ray diffraction (XRD), nano-indentation, and electron microscopy. FT-IR, XRD, and transmission electron microscopy results confirmed the successful synthesis of the nanocomposite and the nanocomposite-incorporated bone cement. The elastic modulus (E) and hardness (H) of the ((Ag/rGO@TiO)/(PS-PMMA)/PMMA) bone cement were measured to be 5.09 GPa and 0.202 GPa, respectively, compared to the commercial counterparts, which exhibited E and H values of 1.7 GPa to 3.7 GPa and 0.174 GPa, respectively. Incorporating Ag/rGO@TiO nanocomposites significantly enhanced the thermal properties of the bone cement. Additionally, in vitro studies demonstrated that the bone cement was non-toxic to the MG63 cell line.
本研究报告了银纳米颗粒/还原氧化石墨烯@二氧化钛纳米复合材料（Ag/rGO@TiO）对聚（苯乙烯-共-甲基丙烯酸甲酯）/聚甲基丙烯酸甲酯（PS-PMMA/PMMA）基骨水泥的力学性能和生物相容性的影响。使用傅里叶变换红外光谱（FT-IR）、X射线衍射（XRD）、纳米压痕和电子显微镜对Ag/rGO@TiO纳米复合材料增强的PS-PMMA骨水泥（（Ag/rGO@TiO）/（PS-PMMA）/PMMA）的化学、结构、力学和热特性进行了评估。FT-IR、XRD和透射电子显微镜结果证实了纳米复合材料以及掺入纳米复合材料的骨水泥的成功合成。（（Ag/rGO@TiO）/（PS-PMMA）/PMMA）骨水泥的弹性模量（E）和硬度（H）分别测量为5.09 GPa和0.202 GPa，相比之下，市售同类产品的E值和H值分别为1.7 GPa至3.7 GPa和0.174 GPa。掺入Ag/rGO@TiO纳米复合材料显著提高了骨水泥的热性能。此外，体外研究表明该骨水泥对MG63细胞系无毒。
