Department of Community and Global Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Department of Epidemiology and Prevention, National Center for Global Health and Medicine, Tokyo, Japan.
Br J Nutr. 2024 Jun 14;131(11):1883-1891. doi: 10.1017/S0007114524000412. Epub 2024 Feb 16.
The literature on green tea consumption and glucose metabolism has reported conflicting findings. This cross-sectional study examined the association of green tea consumption with abnormal glucose metabolism among 3000 rural residents aged 40-60 years in Khánh Hòa province in Vietnam. Multinomial logistic regression analysis was conducted to examine the association of green tea consumption (0, < 200, 200-< 400, 400-< 600 or ≥ 600 ml/d) with prediabetes and diabetes (based on the American Diabetes Association criteria). Linear regression analysis was performed to examine the association between green tea consumption and the log-transformed homeostatic model assessment of insulin resistance (HOMA-IR) (a marker of insulin resistance) and the log-transformed homeostatic model assessment of -cell function (HOMA-) (a marker of insulin secretion). The OR for prediabetes and diabetes among participants who consumed ≥ 600 ml/d . those who did not consume green tea were 1·61 (95 % CI = 1·07, 2·42) and 2·04 (95 % CI = 1·07, 3·89), respectively. Higher green tea consumption was associated with a higher level of log-transformed HOMA-IR ( = 0·04) but not with a lower level of log-transformed HOMA- ( = 0·75). Higher green tea consumption was positively associated with the prevalence of prediabetes, diabetes and insulin resistance in rural Vietnam. The findings of this study indicated prompting the need for further research considering context in understanding the link between green tea consumption and glucose metabolism, especially in rural settings in low- and middle-income countries.
关于绿茶消费与葡萄糖代谢的文献报道结果相互矛盾。本横断面研究调查了在越南庆和省的 3000 名 40-60 岁农村居民中,绿茶消费与异常葡萄糖代谢之间的关系。采用多分类逻辑回归分析来检验绿茶消费(0、<200、200-<400、400-<600 或≥600ml/d)与糖尿病前期和糖尿病(基于美国糖尿病协会标准)之间的关系。进行线性回归分析来检验绿茶消费与稳态模型评估的胰岛素抵抗(HOMA-IR)(胰岛素抵抗的标志物)和稳态模型评估的β细胞功能(HOMA-β)(胰岛素分泌的标志物)的对数值之间的关系。与不饮用绿茶者相比,每天饮用≥600ml/d 绿茶者发生糖尿病前期和糖尿病的 OR 分别为 1.61(95%CI=1.07,2.42)和 2.04(95%CI=1.07,3.89)。较高的绿茶消费与更高水平的 HOMA-IR 的对数值(β=0.04)相关,但与更低水平的 HOMA-β的对数值(β=0.75)无关。较高的绿茶消费与农村越南的糖尿病前期、糖尿病和胰岛素抵抗的患病率呈正相关。本研究结果表明,有必要在考虑到具体情况的前提下,进一步开展研究,以深入了解绿茶消费与葡萄糖代谢之间的关系,尤其是在中低收入国家的农村地区。