Wang Zelong, Lan Xianbin, Fang Yuan, Peng Shaoping, Jin Riqun, Deng Dongming, Song Zhiheng
First Affiliated Hospital of Gannan Medical University, Department of Otolaryngology, Head and Neck Surgery, Jiangxi, China.
First Affiliated Hospital of Gannan Medical University, Department of Otolaryngology, Head and Neck Surgery, Jiangxi, China.
Braz J Otorhinolaryngol. 2025 Jul 29;91(6):101690. doi: 10.1016/j.bjorl.2025.101690.
To evaluate the clinical efficacy of high-frequency electrocautery under electronic laryngoscopy combined with acid-suppressing drugs (Proton Pump Inhibitor, PPI) in the treatment of Refractory Laryngeal Contact Granuloma (RLCG).
A total of 42 patients with RLCG, treated at our hospital from January 2019 to January 2024 were included in this study. The patients underwent high-frequency electrocautery to excise laryngeal granulomas under local anesthesia using electronic laryngoscopy, followed by PPI therapy. Follow-up started one-month post-surgery and lasted for 6-12 months (average of 8.5 months), to assess the cure rate and overall efficacy.
The cure rate was 76.19%, and the overall efficacy rate was 92.86%. On average, each patient underwent 1.79 procedures. The combined treatment of high-frequency electrocautery under local anesthesia with electronic laryngoscopy and PPI therapy demonstrated significant therapeutic effects for RLCG. The treatment was simple, well-tolerated by patients, cost-effective, and resulted in rapid symptom improvement, all without the need for general anesthesia or intubation.
The combined approach of high-frequency electrocautery under local anesthesia with electronic laryngoscopy and PPI therapy is effective in treating refractory laryngeal contact granuloma. This method offers the advantages of a straightforward surgical procedures, high patient tolerance, low cost, quick symptom relief, and no requirement for general anesthesia or intubation.
Level 4-Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence.
评估电子喉镜下高频电灼联合抑酸药物（质子泵抑制剂，PPI）治疗难治性喉接触性肉芽肿（RLCG）的临床疗效。
本研究纳入了2019年1月至2024年1月在我院接受治疗的42例RLCG患者。患者在局部麻醉下使用电子喉镜进行高频电灼切除喉部肉芽肿，随后进行PPI治疗。术后1个月开始随访，持续6 - 12个月（平均8.5个月），以评估治愈率和总体疗效。
治愈率为76.19%，总体有效率为92.86%。平均每位患者接受1.79次手术。局部麻醉下电子喉镜联合PPI治疗对RLCG显示出显著的治疗效果。该治疗方法简单，患者耐受性好，性价比高，症状改善迅速，且无需全身麻醉或插管。
局部麻醉下电子喉镜联合PPI治疗难治性喉接触性肉芽肿有效。该方法具有手术操作简单、患者耐受性高、成本低、症状缓解快以及无需全身麻醉或插管等优点。
牛津循证医学中心2011年证据水平4级。
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