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抑郁和焦虑在黎巴嫩志愿者悲伤反应与创伤后应激症状关系中的中介作用

Mediating Effect of Depression and Anxiety on the Relationship Between Grief Reaction and Post-Traumatic Stress Symptoms in Lebanese Volunteers.

作者信息

Eddine Issa Kamal, Mreydem Hussein Walid, Ayoubi Lemir Majed El, Lee Han-Sung, Salameh Pascale, Chung Seockhoon

机构信息

Department of Family Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

Department of Psychiatry, Bronx Care Health System, Bronx, NY, United States.

出版信息

Psychiatry Investig. 2025 Aug;22(8):870-877. doi: 10.30773/pi.2025.0066. Epub 2025 Jul 31.

Abstract

OBJECTIVE

The Lebanese people have endured through several disasters, such as the Beirut explosion, coronavirus pandemic, and cholera outbreak. However, volunteers who have tried to overcome such national disasters develop emotional stress after witnessing people's death. This study was conducted to explore whether volunteers' depression or anxiety mediates the relationship between grief response and post-traumatic stress disorder (PTSD) symptoms.

METHODS

We conducted an anonymous online survey study and collected responses from 270 volunteers in Lebanon from March 20-26, 2023. Demographic information and responses to the questionnaires, which included the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), Post-Traumatic Stress Disorder Checklist for DSM-5 (PCL-5), Public Service Motivation scale (PSM scale), Connor-Davidson Resilience Scale-2, and Prolonged Grief Disorder (PG-13) were collected. Variables were compared between volunteers who did and did not witness people's death. Furthermore, we explored the relationships among variables in volunteers who witnessed people's death (n=72).

RESULTS

Among 270 participants, 72 (26.67%) witnessed people's death. The regression model demonstrated that scores for PG-13 (β= 0.31, p<0.001), PHQ-9 (β=0.21, p=0.011), and GAD-7 (β=0.44, p<0.001) were predictors of the PCL-5 score. Mediation analysis showed that grief reaction directly influenced PTSD symptoms (Z=6.19, p<0.001), whereas depression (Z=1.99, p=0.047) and anxiety (Z=2.79, p=0.005) individually mediated the relationship between grief reaction and PTSD symptoms.

CONCLUSION

Our study helps understand the mediating effects of volunteers' depression or anxiety on the relationship between grief reactions and PTSD symptoms.

摘要

目的

黎巴嫩人民经历了几次灾难,如贝鲁特爆炸、新冠疫情和霍乱疫情。然而,试图克服此类国家灾难的志愿者在目睹人们死亡后会产生情绪压力。本研究旨在探讨志愿者的抑郁或焦虑是否介导了悲伤反应与创伤后应激障碍(PTSD)症状之间的关系。

方法

我们进行了一项匿名在线调查研究,于2023年3月20日至26日收集了黎巴嫩270名志愿者的回复。收集了人口统计学信息以及对问卷的回复,这些问卷包括患者健康问卷-9(PHQ-9)、广泛性焦虑障碍量表-7(GAD-7)、DSM-5创伤后应激障碍检查表(PCL-5)、公共服务动机量表(PSM量表)、康纳-戴维森韧性量表-2和持续性悲伤障碍量表(PG-13)。对目睹和未目睹人们死亡的志愿者的变量进行了比较。此外,我们探讨了目睹人们死亡的志愿者(n = 72)中各变量之间的关系。

结果

在270名参与者中,72人(26.67%)目睹了人们的死亡。回归模型表明,PG-13得分(β = 0.31,p < 0.001)、PHQ-9得分(β = 0.21,p = 0.011)和GAD-7得分(β = 0.44,p < 0.001)是PCL-5得分的预测因素。中介分析表明,悲伤反应直接影响PTSD症状(Z = 6.19,p < 0.001),而抑郁(Z = 1.99,p = 0.047)和焦虑(Z = 2.79,p = 0.005)分别介导了悲伤反应与PTSD症状之间的关系。

结论

我们的研究有助于理解志愿者的抑郁或焦虑对悲伤反应与PTSD症状之间关系的中介作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/12370431/c740bdca953a/pi-2025-0066f1.jpg

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