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在新冠疫情期间的非工作时间服务中诊断急性下呼吸道感染

Diagnosing acute lower respiratory tract infections in out-of-hours services during the COVID-19 pandemic.

作者信息

Lindberg Bent Håkan, López-Valcárcel Beatriz González, Olsen Jonas K, Hansen Malene Plejdrup, Lykkegaard Jesper, Llor Carl, Jaruseviciene Lina, Pascale Bruno, Karkana Maria-Nefeli, García-Sangenís Ana, Kowalczyk Anna, Rebnord Ingrid

机构信息

National Centre for Emergency Primary Health Care, NORCE Norwegian Research Centre AS, Nygårdstangen, PO Box 22, Bergen, N-5838 , Norway.

Dep. of General Practice, Inst. of Health and Society, University of Oslo, Oslo, Norway.

出版信息

Int J Emerg Med. 2025 Jul 30;18(1):138. doi: 10.1186/s12245-025-00942-z.

Abstract

BACKGROUND

Acute lower respiratory tract infections (LRTIs) commonly lead people to seek out-of-hours primary care. Symptoms of lower respiratory tract infections overlap, and access to definite diagnostic tools is lacking in most out-of-hours settings. Distinguishing between different LRTIs is vital to ensure appropriate antibiotic prescribing. The study aimed to identify which clinical factors have guided out-of-hours physicians in distinguishing LRTIs in the late phase of the COVID-19 pandemic.

METHODS

Out-of-hours physicians from France, Greece, Lithuania, Poland, and Spain registered pre-defined clinical information about all cases suspected of an RTI on an A4-paper Audit Project Odense chart from January to March 2022. Two multivariable logistic regressions were performed to analyse which clinical factors the physicians used to distinguish between pneumonia and other LRTIs.

RESULTS

A total of 1,222 cases of either pneumonia, acute bronchitis/bronchiolitis, common cold/influenza, or COVID-19 were registered by 86 participating physicians. Fever and cough were the most common symptoms reported. The pneumonia diagnosis was associated with abnormal lung auscultation (odds ratio (OR) 11.41, 95% confidence interval (CI) 4.14-31.45), poor general condition (OR 5.96, CI 2.43-14.60), tachypnoea (OR 2.55, CI 1.38-4.73), and a combination of fever and cough (OR 11.10, CI 2.87-42.97).

CONCLUSION

During the late COVID-19 pandemic, out-of-hours physicians' registered information about the patients' clinical condition, respiratory rate assessment, and lung auscultation evaluation were associated with diagnosing pneumonia, among other LRTIs.

摘要

背景

急性下呼吸道感染(LRTIs)常导致人们寻求非工作时间的初级医疗服务。下呼吸道感染的症状相互重叠,且在大多数非工作时间的环境中缺乏明确的诊断工具。区分不同的LRTIs对于确保合理使用抗生素至关重要。本研究旨在确定在新冠疫情后期,哪些临床因素指导了非工作时间的医生区分LRTIs。

方法

来自法国、希腊、立陶宛、波兰和西班牙的非工作时间医生在2022年1月至3月期间,将所有疑似呼吸道感染病例的预定义临床信息记录在奥登塞A4纸审核项目图表上。进行了两个多变量逻辑回归分析,以分析医生用于区分肺炎和其他LRTIs的临床因素。

结果

86名参与医生共记录了1222例肺炎、急性支气管炎/细支气管炎、普通感冒/流感或新冠病例。发热和咳嗽是最常见的报告症状。肺炎诊断与肺部听诊异常(比值比(OR)11.41,95%置信区间(CI)4.14 - 31.45)、一般状况差(OR 5.96,CI 2.43 - 14.60)、呼吸急促(OR 2.55,CI 1.38 - 4.73)以及发热和咳嗽同时出现(OR 11.10,CI 2.87 - 42.97)有关。

结论

在新冠疫情后期,非工作时间医生记录的患者临床状况、呼吸频率评估和肺部听诊评估信息与诊断肺炎及其他LRTIs有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/351f/12312447/b9bcc758d94c/12245_2025_942_Fig1_HTML.jpg

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