Somlyo A P, Urbanics R, Vadasz G, Kovach A G, Somlyo A V
Biochem Biophys Res Commun. 1985 Nov 15;132(3):1071-8. doi: 10.1016/0006-291x(85)91916-3.
Mitochondrial calcium in rat brain cortex frozen in situ and measured with electron probe X-ray microanalysis was 1.5 mmol Ca/kg dry weight. Cellular, extramitochondrial Ca was 6.4mmol/kg dry weight and cytoplasmic Na+ was 73mM. These results do not support the role of mitochondria regulating cytoplasmic Ca2+, but are compatible with the regulation of mitochondrial enzymes by matrix free Ca2+.
