Turpin Andrew, Morgan William H, McKendrick Allison M
Lions Eye Institute, Perth, Australia.
School of Population Health, Curtin University, Perth Australia.
Transl Vis Sci Technol. 2025 Aug 1;14(8):1. doi: 10.1167/tvst.14.8.1.
The decision to switch between peripheral (24-2) and central (10-2) visual field testing in glaucoma currently rests with clinicians and requires a choice between either intensively sampling central vision or including testing of more peripheral locations (not both). We evaluate an automated approach to incorporate 10-2 locations into the 24-2, without increasing test time or reducing the ability to detect glaucomatous progression at the 24-2 locations.
We applied our previously published ARREST approach, restricting added locations to a 10-2 pattern (A10). Using computer simulation, the sensitivity of A10 for detecting progression was compared to a ZEST procedure on the 24-2 pattern. Input fields were a synthetic series of 10 visits (6 monthly) of 126 eyes, derived from empirical longitudinal 24-2 data from people with glaucoma.
Forty-seven of the 126 progressing visual field series had locations added by A10. The procedures used a similar number of presentations (mean ± SD: A10, 220 ± 27; ZEST, 226 ± 29). Area under the curve (AUC) and survival time for detecting progressing series were similar between methods. A10 allowed visualization of the macular visual field with higher fidelity.
The A10 approach allows automated incorporation of 10-2 locations into the 24-2 pattern that are customized to individuals without increasing test times.
The A10 enables higher spatial sampling in individually relevant areas of the 10-2, without neglecting testing of the more peripheral visual field.
目前青光眼患者从周边视野（24-2）检测切换至中央视野（10-2）检测的决定由临床医生做出，且需要在密集采样中央视野或纳入更多周边位置检测（二者不可兼顾）之间进行选择。我们评估一种自动化方法，将10-2位置纳入24-2检测中，同时不增加检测时间或降低在24-2位置检测青光眼进展的能力。
我们应用之前发表的ARREST方法，将添加的位置限制为10-2模式（A10）。通过计算机模拟将A10检测进展的敏感性与24-2模式下的ZEST程序进行比较。输入视野是从青光眼患者的经验性纵向24-2数据得出的126只眼睛的10次就诊（每6个月一次）的合成系列。
126个进展性视野系列中有47个系列的位置由A10添加。两种程序使用的呈现次数相似（均值±标准差：A10，220±27；ZEST，226±29）。两种方法在检测进展性系列的曲线下面积（AUC）和生存时间方面相似。A10能以更高的保真度显示黄斑视野。
A10方法可将10-2位置自动纳入24-2模式，且针对个体进行定制，同时不增加检测时间。
A10能够在10-2的个体相关区域进行更高空间采样，而不会忽略对更周边视野的检测。
