Novitskiĭ V V, Fursov S E, Gol'dberg E D
Biull Eksp Biol Med. 1985 Dec;100(12):718-9.
The reserve potentialities of granulocyto- and erythropoesis were studied in noninbred rats and BALB/c mice using morphological functional methods and various compensatory-functional simulators of hemopoiesis strain 1.3 and 6 months after treatment with rubomycin at a therapeutic dose of 1.5 mg/kg. The animals were found to retain limited granulocyto- and erythropoesis compensatory reactions to additional hemopoesis-disturbing influences in spite of complete recovery of hematopoetic stem-cell pool, bone marrow and peripheral blood cell composition at remote terms after treatment.
使用形态功能方法和造血的各种代偿功能模拟器，在非近交系大鼠和BALB/c小鼠中研究了粒细胞生成和红细胞生成的储备潜力。这些动物在以1.5mg/kg治疗剂量的柔红霉素治疗后1.3和6个月。尽管在治疗后的远期造血干细胞库、骨髓和外周血细胞组成已完全恢复，但发现这些动物对额外的造血干扰影响仍保留有限的粒细胞生成和红细胞生成代偿反应。
