Ratajczak Piotr, Jacieczko Barbara, Kędziora Bartosz, Kopciuch Dorota, Paczkowska Anna, Zaprutko Tomasz, Kus Krzysztof
Department of Pharmacoeconomics and Social Pharmacy, Poznan University of Medical Sciences, Poznań, Poland.
Collegium Medicum, Jan Kochanowski University, Kielce, Poland.
PLoS One. 2025 Aug 1;20(8):e0329016. doi: 10.1371/journal.pone.0329016. eCollection 2025.
Applying Evidence-Based Pharmacy (EBPharm) principles is essential in pharmacy practice as it allows therapeutic decisions to be grounded in the best available scientific evidence. This approach enables pharmacists to provide patients with more effective and safer therapies, reducing the risk of adverse effects. This study assessed the EBPharm knowledge level among pharmacy professionals. Data were collected using a custom-designed online survey. The study also explored and defined the concept of EBPharm, offering insights into medical databases, types of scientific research, and evaluations of their quality and reliability. The study revealed widespread application of EBPharm principles among Polish pharmacy professionals, with significant associations between their use and factors such as professional experience (Chi² = 7.905518, p = 0.04801) and higher salaries. Respondents with formal EBPharm training demonstrated improved ability to evaluate scientific evidence (Chi² = 12.03125, p = 0.00244), while financial stability was linked to better systematic review skills (Chi² = 43.15693, p = 0.00000) and use of databases (Chi² = 63.14029, p = 0.00000). However, knowledge gaps remain, particularly among less experienced professionals, with only 30.35% of participants receiving formal training and 8.42% deeming it sufficient. Frequent use of informal sources by pharmacy technicians and limited familiarity with frameworks like PICO (Chi² = 37.65817, p = 0.00000) highlight the need for accessible, structured education. Targeted training, financial incentives, and greater reliance on reliable sources could enhance EBPharm integration, improving care quality and patient safety.
应用循证药学（EBPharm）原则在药学实践中至关重要，因为它能使治疗决策基于现有最佳科学证据。这种方法使药剂师能够为患者提供更有效、更安全的治疗，降低不良反应风险。本研究评估了药学专业人员的循证药学知识水平。数据通过定制的在线调查问卷收集。该研究还探索并定义了循证药学的概念，深入了解了医学数据库、科研类型以及对其质量和可靠性的评估。研究表明，循证药学原则在波兰药学专业人员中得到广泛应用，其使用与专业经验（卡方值=7.905518，p=0.04801）和较高薪资等因素之间存在显著关联。接受过循证药学正式培训的受访者评估科学证据的能力有所提高（卡方值=12.03125，p=0.00244），而财务稳定性与更好的系统评价技能（卡方值=43.15693，p=0.00000）和数据库使用（卡方值=63.14029，p=0.00000）相关。然而，知识差距仍然存在，尤其是在经验较少的专业人员中，只有30.35%的参与者接受过正式培训，且8.42%的人认为培训足够。药房技术人员频繁使用非正式来源，且对PICO等框架的熟悉程度有限（卡方值=37.65817，p=0.00000），这凸显了提供易于获取的结构化教育的必要性。有针对性的培训、经济激励以及更多地依赖可靠来源可以加强循证药学的整合，提高护理质量和患者安全。
