Andersen Trine B, Braun Elliot, Brown Brianna N I, Hamberger Bjoern, Knoor Leah, Korkmaz İlayda, Reist Lucas, Sharpe Luke, McKinley Brian Adam, Suggitt James O, Ticoras Mitchell A, Indibi Angel
Molecular Plant Sciences Program, Michigan State University, East Lansing, Michigan, 48824, USA.
DOE Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, Michigan, 48824, USA.
Biotechnol Lett. 2025 Aug 1;47(4):85. doi: 10.1007/s10529-025-03623-2.
Biofuels generated through fermentation of plant-derived lignocellulosic biomass are currently not competitive with fossil fuels. Here, a framework is described for the engineering of valuable coproducts to improve the economic feasibility of biofuel production. To accomplish this goal, the desirable traits of the bioenergy crop Sorghum bicolor are harnessed via modern engineering approaches. A robust analysis is provided to highlight the scientific basis, costs, regulatory challenges, and lucrative nature of coproduct development. Sustainable biofuel production could also have far-reaching societal impacts, especially in the context of our rapidly changing global climate. This perspective suggests that the path to profitable biofuel production is attainable and encourages consideration of similar approaches by the biotechnology industry.
通过植物源木质纤维素生物质发酵产生的生物燃料目前在与化石燃料的竞争中不占优势。本文描述了一个用于设计有价值的副产品以提高生物燃料生产经济可行性的框架。为实现这一目标，通过现代工程方法利用生物能源作物双色高粱的理想特性。提供了一项全面的分析，以突出副产品开发的科学依据、成本、监管挑战和盈利性质。可持续生物燃料生产也可能产生深远的社会影响，特别是在我们迅速变化的全球气候背景下。这一观点表明，实现盈利性生物燃料生产的途径是可行的，并鼓励生物技术行业考虑类似的方法。
