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院外疑似阿片类药物相关心脏骤停时旁观者干预的障碍:一项对911电话的多方法研究

Barriers to bystander interventions in suspected opioid-associated out-of-hospital cardiac arrests: A multiple methods study of 9-1-1 calls.

作者信息

Joiner Anjni, Kamara Memu-Iye, Powell Stephen, Hart Lauren, Sawin Gregory, Glenn Melody, Vleet Lee Van, Supples Michael, Chan Brian, Starks Monique, Blewer Audrey L

机构信息

Department of Emergency Medicine, Duke University School of Medicine, 2301 Erwin Rd Box 3096, Durham, NC 27710, USA; Durham County Emergency Medical Services, 201 E Main St, Ste 660, Durham, NC 27701, USA.

Department of Emergency Medicine, East Carolina University School of Medicine, 600 Moye Blvd, Greenville, NC 27834, USA; Pitt County Emergency Management, 1717 W 5th St, Greenville, NC 27834, USA.

出版信息

Resuscitation. 2025 Aug 5;215:110748. doi: 10.1016/j.resuscitation.2025.110748.

DOI:10.1016/j.resuscitation.2025.110748
PMID:40752676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12376069/
Abstract

INTRODUCTION

Opioid-associated out-of-hospital cardiac arrests (OA-OHCA) is a significant problem in the United States. Layperson interventions, including bystander CPR and naloxone may improve survival, but barriers may differ compared to other OHCA. This study aims to describe characteristics of 9-1-1 callers and patients in suspected OA-OHCAs and identify barriers to B-CPR and naloxone administration.

METHODS

This was a retrospective multiple methods study of transcribed 9-1-1 calls for suspected OHCA from two counties in North Carolina (5/2022-12/2023). Adult, non-traumatic OHCAs were included. Data were analyzed using descriptive statistics and Student's t-test/Chi. We used thematic analysis and a combined deductive and inductive approach.

RESULTS

Patients with suspected OA-OHCA were younger than non-suspected OA-OHCA patients (39 vs 58 years [p < 0.01]). Most patients were in a residence, however, this percentage was smaller in suspected OA-OHCA compared with non-suspected OA-OHCA (68 % vs 88 % [p < 0.01]). Most callers in the suspected OA-OHCA group were a friend of the patient (35 %), whereas most callers in the non-suspected OA-OHCA population were a family member (34 %) [p < 0.01]. Qualitative barriers unique to suspected OA-OHCA included: conflicting responsibilities, fear of drugs, and fear of the patient. Naloxone-specific barriers included lack of availability and lack of knowledge of use.

CONCLUSION

We found significant differences in demographics between suspected OA-OHCA compared with non-suspected OA-OHCA. We also identified unique barriers in this population as well as previously described barriers which may be amplified in the setting of suspected drug use. A different approach towards cardiac resuscitation may be needed to maximize treatment and survival.

摘要

引言

阿片类药物相关的院外心脏骤停(OA-OHCA)在美国是一个重大问题。包括旁观者心肺复苏(CPR)和纳洛酮在内的非专业人员干预可能会提高生存率,但与其他院外心脏骤停相比,障碍可能有所不同。本研究旨在描述疑似OA-OHCA事件中911呼叫者和患者的特征,并确定旁观者心肺复苏和纳洛酮给药的障碍。

方法

这是一项回顾性多方法研究,对北卡罗来纳州两个县(2022年5月至2023年12月)疑似院外心脏骤停的911电话录音进行分析。纳入成人非创伤性院外心脏骤停病例。数据采用描述性统计和学生t检验/卡方检验进行分析。我们采用了主题分析以及演绎与归纳相结合的方法。

结果

疑似OA-OHCA的患者比非疑似OA-OHCA的患者更年轻(39岁对58岁[p<0.01])。大多数患者在家中,但与非疑似OA-OHCA相比,疑似OA-OHCA患者在家中的比例更小(68%对88%[p<0.01])。疑似OA-OHCA组的大多数呼叫者是患者的朋友(35%),而非疑似OA-OHCA人群中的大多数呼叫者是家庭成员(34%)[p<0.01]。疑似OA-OHCA特有的定性障碍包括:责任冲突、对药物的恐惧和对患者的恐惧。纳洛酮特有的障碍包括无法获得和缺乏使用知识。

结论

我们发现疑似OA-OHCA与非疑似OA-OHCA在人口统计学上存在显著差异。我们还确定了该人群中独特的障碍以及先前描述的可能在疑似药物使用情况下加剧的障碍。可能需要采取不同的心脏复苏方法以最大限度地提高治疗效果和生存率。