在无细胞系统中重建内吞融合事件。
Reconstitution of an endocytic fusion event in a cell-free system.
作者信息
Davey J, Hurtley S M, Warren G
出版信息
Cell. 1985 Dec;43(3 Pt 2):643-52. doi: 10.1016/0092-8674(85)90236-3.
PMID:4075403
Abstract
Using a cell-free system we have obtained fusion of vesicles from the endocytic pathway. The fusion is rapid, efficient, and requires ATP. Only vesicles derived from certain positions along the endocytic pathway are capable of fusing. Lysosomes and vesicles derived from the plasma membrane do not fuse.
摘要
利用无细胞系统，我们实现了来自内吞途径的囊泡融合。这种融合迅速、高效且需要ATP。只有来自内吞途径中特定位置的囊泡能够融合。溶酶体和源自质膜的囊泡不会融合。
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