Shukla Noynika, Latha A Tharuni, R Manjunath P, J M Sanjana, Panju Santhosh, B K Kavya
Endocrinology, Diabetes and Metabolism, Ramaiah Medical College and Hospital, Bengaluru, IND.
Internal Medicine, Ramaiah Medical College, Bengaluru, IND.
Cureus. 2025 Jul 3;17(7):e87234. doi: 10.7759/cureus.87234. eCollection 2025 Jul.
Systemic hypertension (HTN) is one of the most common comorbidities in diabetes mellitus (DM). Diabetic patients with HTN have a several-fold increased risk of cardiovascular disease (CVD) as compared to normotensive nondiabetic controls. Routine office blood pressure (BP) measurement does not help diagnose hypertensive phenotypes such as masked hypertension, white coat hypertension, etc. Hence, ambulatory blood pressure monitoring (ABPM) is a valuable tool for diagnosing these conditions, as it can help identify adverse cardiovascular complications.
To study the patterns of ambulatory blood pressure profile in normotensive patients with type 2 DM.
This was a cross-sectional study conducted among all patients aged 18 years and above who attended the endocrinology outpatient department of a tertiary care hospital.
The total number of participants in the study was 57, with a mean age of 55.26 years (SD 13.52) among patients. Males comprised the majority, at 32 (56.1%). Masked hypertension was found in 22 (38.6%) patients who had normal blood pressure on routine office BP measurements. Among the masked hypertensive group, 10 (45.5%) patients were dippers, nine (40.9%) were non-dippers, and the rest were reverse dippers. Of those with masked hypertension, 4.54% (n=1) had isolated daytime hypertension, 31.8% (n=7) had isolated nocturnal hypertension, and 63.63% (n=14) had both. Age was the factor that influenced masked hypertension in the study.
The present study underscores the need to incorporate routine utilization of ambulatory blood pressure monitoring in patients with type 2 DM for early identification of hypertension. Solely depending upon office blood pressure monitoring might not be sufficient to detect the hypertensive phenotypes in patients with type 2 DM.
系统性高血压(HTN)是糖尿病(DM)最常见的合并症之一。与血压正常的非糖尿病对照组相比,患有高血压的糖尿病患者患心血管疾病(CVD)的风险增加了几倍。常规诊室血压(BP)测量无助于诊断隐匿性高血压、白大衣高血压等高血压表型。因此,动态血压监测(ABPM)是诊断这些情况的重要工具,因为它有助于识别不良心血管并发症。
研究2型糖尿病血压正常患者的动态血压模式。
这是一项横断面研究,在一家三级医院内分泌科门诊就诊的所有18岁及以上患者中进行。
研究参与者总数为57人,患者平均年龄为55.26岁(标准差13.52)。男性占多数,为32人(56.1%)。在常规诊室血压测量中血压正常的22名(38.6%)患者中发现了隐匿性高血压。在隐匿性高血压组中,10名(45.5%)患者为杓型血压,9名(40.9%)为非杓型血压,其余为反杓型血压。在隐匿性高血压患者中,4.54%(n = 1)为单纯日间高血压,31.8%(n = 7)为单纯夜间高血压,63.63%(n = 14)两者皆有。年龄是该研究中影响隐匿性高血压的因素。
本研究强调了在2型糖尿病患者中常规使用动态血压监测以早期识别高血压的必要性。仅依靠诊室血压监测可能不足以检测2型糖尿病患者的高血压表型。