Hebib Lana, Gustafson Hedov Emelie, Storgärds Maria, Af Geijerstam Peder, Löf Marie, Wu Jason Hy, Kastbom Lisa, Rådholm Karin
Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Digit Health. 2025 Jul 31;11:20552076251365063. doi: 10.1177/20552076251365063. eCollection 2025 Jan-Dec.
Digital tools and self-administered home blood tests offer a flexible approach to research data collection, biological sample management, and informed consent but require evaluation in relevant study settings. This study explored user experiences with a web-based digital tool for trial management, symptom reporting, and home blood testing.
Forty-three middle-aged participants took part in a 12-week mixed-method study, using digital tools for trial management, self-reported health data, and self-administered glycated hemoglobin A1c home blood tests. Usability was assessed through the validated mHealth App Usability Questionnaire (MAUQ) with additional study-specific items. Every second participant completed a semi-structured interview, analyzed using qualitative content analysis.
The MAUQ responses (scale 1-7) indicated that digital consent (94.7% agreed), and home blood tests (100% agreed) were well-received. However, finding information on digital tools was challenging (52.9% disagreed it was easy), and participants did not perceive the tools highly effective for managing health (52.9% disagreed they were helpful). Interviews with 20 participants reinforced these findings, emphasizing motivation, support, efficient resource use, and the importance of clarity, usability, safety, and security.
While self-administered blood tests and online consent were considered user-friendly, improvements are needed in digital tool navigation and information accessibility to enhance usability in decentralized trials, especially for participants who find them difficult or unhelpful.
数字工具和自我管理的家庭血液检测为研究数据收集、生物样本管理和知情同意提供了一种灵活的方法，但需要在相关研究环境中进行评估。本研究探讨了用户使用基于网络的数字工具进行试验管理、症状报告和家庭血液检测的体验。
43名中年参与者参加了一项为期12周的混合方法研究，使用数字工具进行试验管理、自我报告健康数据和自我管理糖化血红蛋白A1c家庭血液检测。通过经过验证的移动健康应用程序可用性问卷（MAUQ）以及其他特定于研究的项目来评估可用性。每隔一名参与者完成一次半结构化访谈，并使用定性内容分析进行分析。
MAUQ的回答（1-7分制）表明，数字同意（94.7%同意）和家庭血液检测（100%同意）受到好评。然而，查找数字工具上的信息具有挑战性（52.9%不同意这很容易），并且参与者认为这些工具在管理健康方面效果不佳（52.9%不同意它们有帮助）。对20名参与者的访谈强化了这些发现，强调了动机、支持、有效资源利用以及清晰度、可用性、安全性和保障的重要性。
虽然自我管理的血液检测和在线同意被认为对用户友好，但在数字工具导航和信息可及性方面仍需改进，以提高分散试验中的可用性，特别是对于那些觉得它们困难或无用的参与者。
