Farghaly Mohamed Ashraf, Nasreldin Hadeer Mohamed, Saafan Ali Mohamed, Arafat Ahmed Ezzat, Abdullateef Khaled S, Kaddah Sherif Nabhan, Wishahy Ahmed Mohamed
Department of Paediatric Surgery, Cairo University Specialized Paediatric Hospital, Cairo University, Cairo, Egypt.
National Laser Institute, Cairo University, Giza, Egypt.
J Indian Assoc Pediatr Surg. 2025 Jul-Aug;30(4):464-468. doi: 10.4103/jiaps.jiaps_257_24. Epub 2025 Jun 6.
Infantile hemangiomas affect 4%-10% of children under 1 year, while venous malformations (VMs) occur in 1-5/10,000 births. Oral hemangiomas (OHs) often ulcerate and lead to complications, whereas VMs can cause significant morbidity through bleeding, painful expansion, or obstruction of vital structures. Early and effective treatment is crucial, and intralesional diode laser therapy has been proposed as a promising intervention.
A prospective interventional cohort was conducted on 40 patients: 29 patients with OH and 11 patients with oral VMs at the pediatric surgery department of Cairo University Children Hospital. A 980-nm diode laser (Lasotronix-Smart M) was used for intralesional coagulation and excision. Outcomes, including lesion size, color improvement, and patient-reported satisfaction, were assessed at 1- and 6-month posttreatment.
The median pretreatment lesion size of 16.5 mm significantly decreased to 13.2 mm ( < 0.01). Color improvement was observed as normal in 25% of cases, near normal in 52.5%, slight improvement in 17.5%, and no change in 5%. Fifty percent of patients reported their condition as "much better." Complications included edema in 87.5%, ulceration in 30%, bleeding in 7.5%, infection in 7.5%, and recurrence in 2.5%.
Intralesional diode laser therapy is a safe and effective modality for managing OHs and VMs in children, providing significant cosmetic and functional benefits with a low recurrence rate.
婴儿血管瘤影响4% - 10%的1岁以下儿童，而静脉畸形（VMs）的发病率为每10000例出生中有1 - 5例。口腔血管瘤（OHs）常发生溃疡并导致并发症，而VMs可通过出血、疼痛性扩张或重要结构梗阻引起严重病变。早期有效治疗至关重要，瘤内二极管激光治疗已被提出作为一种有前景的干预措施。
在开罗大学儿童医院小儿外科对40例患者进行了一项前瞻性干预队列研究：29例OH患者和11例口腔VM患者。使用980纳米二极管激光（Lasotronix - Smart M）进行瘤内凝固和切除。在治疗后1个月和6个月评估结果，包括病变大小、颜色改善情况以及患者报告的满意度。
治疗前病变大小中位数为16.5毫米，显著降至13.2毫米（<0.01）。25%的病例颜色改善为正常，52.5%接近正常，17.5%略有改善，5%无变化。50%的患者报告病情“好多了”。并发症包括87.5%的水肿、30%的溃疡、7.5%的出血、7.5%的感染以及2.5%的复发。
瘤内二极管激光治疗是治疗儿童OHs和VMs的一种安全有效的方法，具有显著的美容和功能益处，复发率低。
