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葡萄酒色斑的激光治疗。

Laser treatment of port-wine stains.

作者信息

Brightman Lori A, Geronemus Roy G, Reddy Kavitha K

机构信息

Laser and Skin Surgery Center of New York, New York, NY, USA.

Department of Dermatology, Boston University School of Medicine, Boston, MA, USA.

出版信息

Clin Cosmet Investig Dermatol. 2015 Jan 12;8:27-33. doi: 10.2147/CCID.S53118. eCollection 2015.

DOI:10.2147/CCID.S53118
PMID:25624768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4296879/
Abstract

Port-wine stains are a type of capillary malformation affecting 0.3% to 0.5% of the population. Port-wine stains present at birth as pink to erythematous patches on the skin and/or mucosa. Without treatment, the patches typically darken with age and may eventually develop nodular thickening or associated pyogenic granuloma. Laser and light treatments provide improvement through selective destruction of vasculature. A variety of vascular-selective lasers may be employed, with the pulsed dye laser being the most common and well studied. Early treatment produces more optimal results. Advances in imaging and laser treatment technologies demonstrate potential to further improve clinical outcomes.

摘要

葡萄酒色斑是一种影响0.3%至0.5%人群的毛细血管畸形。葡萄酒色斑在出生时表现为皮肤和/或黏膜上粉红色至红斑样斑块。未经治疗,这些斑块通常会随着年龄增长而变暗,并最终可能出现结节性增厚或相关的化脓性肉芽肿。激光和光治疗通过选择性破坏血管来改善病情。可使用多种血管选择性激光,其中脉冲染料激光最为常用且研究充分。早期治疗能产生更优的效果。成像和激光治疗技术的进步显示出进一步改善临床结果的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/4296879/1aef41b08c52/ccid-8-027Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/4296879/f6d8c789905c/ccid-8-027Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/4296879/c14b63c74cb0/ccid-8-027Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/4296879/1aef41b08c52/ccid-8-027Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/4296879/f6d8c789905c/ccid-8-027Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/4296879/c14b63c74cb0/ccid-8-027Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/4296879/1aef41b08c52/ccid-8-027Fig3.jpg

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Lasers Surg Med. 2014 Nov;46(9):679-88. doi: 10.1002/lsm.22296. Epub 2014 Sep 30.
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Sustained activation of c-Jun N-terminal and extracellular signal-regulated kinases in port-wine stain blood vessels.
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