Garcia Charlotte, Sismono Fergio, Goehring Tobias, Guérit François, Arzounian Dorothée, Carlyon Robert P
Cambridge Hearing Group, MRC Cognition & Brain Sciences Unit, University of Cambridge, Cambridge, CB17EF, United Kingdom.
European Institute for ORL-HNS (EIORL) ZAS Augustinus, Oosterveldlaan 24, 2610 Wilrijk - Antwerp,
JASA Express Lett. 2025 Aug 1;5(8). doi: 10.1121/10.0038746.
The health of the auditory nerve is a key factor for hearing outcomes in cochlear-implant patients. Many electrophysiological markers of auditory-neural health have been proposed, with varying predictive power and independence from non-neural factors. The "Failure Index" (FI), the ratio between stimulation current level and response magnitude of the electrically-evoked compound action potential (eCAP) was compared to the Panoramic eCAP method. Both methods predicted localized areas of reduced neural responsiveness in a group of human cochlear-implant users, but the FI showed a greater dependence on a non-neural factor, namely, the distances between the cochlear-implant electrodes and the auditory nerves.
听神经的健康状况是影响人工耳蜗植入患者听力结果的关键因素。人们已经提出了许多听神经健康的电生理指标，其预测能力和不受非神经因素影响的程度各不相同。将“失败指数”（FI），即刺激电流水平与电诱发复合动作电位（eCAP）反应幅度之比，与全景eCAP方法进行了比较。两种方法都能预测一组人工耳蜗植入使用者中神经反应性降低的局部区域，但FI对一个非神经因素，即人工耳蜗电极与听神经之间的距离，表现出更大的依赖性。
