Comparison of the pharmacokinetic profile of metaclazepam in old and young volunteers.
作者信息
Molz K H, Gielsdorf W, Rasper J, Jaeger H, Hausleiter H J, Achtert G, Philipp P
出版信息
Eur J Clin Pharmacol. 1985;29(2):247-9. doi: 10.1007/BF00547431.
PMID:4076323
Abstract
A single-centre, open, Phase I-study comparison of the pharmacokinetics of a single dose of metaclazepam 10 mg, a new 1,4-benzodiazepine has been done in 10 older and 20 younger volunteers. No important age-related effect was found on the kinetics of metaclazepam or its N-desmethyl derivative, the principal metabolite in man.
摘要
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