Biljana Kuzmanović Elabjer, Tea Štrbac, Iva Ćubela, Benedict Rak, Dora Martinčević, Mladen Bušić, Mirjana Bjeloš
University Eye Department, University Hospital "Sveti Duh", Zagreb, Croatia / Reference center of the Ministry of Health of the Republic of Croatia for Pediatric Ophthalmology and Strabismus / Reference center of the Ministry of Health of the Republic of Croatia for Inherited Retinal Dystrophies / Reference center of the Ministry of Health of the Republic of Croatia for Standardized Echography in Ophthalmology.
Faculty of Medicine Osijek, Faculty of Dental Medicine and Health Osijek, University Josip Juraj Strossmayer in Osijek, Croatia.
Korean J Ophthalmol. 2025 Aug 6. doi: 10.3341/kjo.2025.0072.
The purpose of this study is to determine which demographic and biometric factors, lens hardness, complications such as PEX and IFIS, and intraoperative metrics have the greatest influence on Active Surge Mitigation (ASM) actuation during phacoemulsification using the Centurion® Vision System with the ACTIVE SENTRY® Handpiece.
The preoperative analysis considered age, gender, biometric data (obtained using the Zeiss IOL Master 700 and Oculus Pentacam), and lens hardness according to the Lens Opacification Classification System (LOCS III). Intraoperative Floppy Iris Syndrome (IFIS) and Pseudoexfoliation Syndrome (PEX) were also assessed. Intraoperative metrics during phacoemulsification included total case time, cumulative dissipated energy (CDE), total ultrasound time (U/S time), and the number of active surge mitigation (ASM) actuations.
Significant positive correlations were found between ASM and both LOCS (P=0.001) and age (P=0.017), albeit a significant negative correlation was observed with anterior chamber depth (ACD) (P=0.005). No significant differences in the number of ASM actuations were observed between genders or in patients with PEX or IFIS. In multivariate analysis, an ASM ≥ 1 significantly predicted higher LOCS (OR 1.79, 95% CI 1.04-2.95), whereas greater ACD reduced this likelihood (OR 0.311, 95% CI 0.100-0.960).
ASM actuation is more frequent with advanced lens hardness and old age, while a deep anterior chamber reduces actuations compared to a shallow one. Lens hardness affects ASM more than anterior chamber depth, and no significant correlation was found between PEX, IFIS, and ASM.
本研究的目的是确定哪些人口统计学和生物特征因素、晶状体硬度、诸如假性剥脱综合征(PEX)和虹膜松弛综合征(IFIS)等并发症以及术中指标,在使用配备ACTIVE SENTRY®手持件的Centurion®视觉系统进行超声乳化手术期间,对主动浪涌缓解(ASM)启动影响最大。
术前分析考虑了年龄、性别、生物特征数据(使用蔡司IOL Master 700和欧科路Pentacam获得)以及根据晶状体混浊分类系统(LOCS III)的晶状体硬度。还评估了术中虹膜松弛综合征(IFIS)和假性剥脱综合征(PEX)。超声乳化手术期间的术中指标包括总手术时间、累积消散能量(CDE)、总超声时间(超声时间)以及主动浪涌缓解(ASM)启动次数。
ASM与LOCS(P = 0.001)和年龄(P = 0.017)之间均存在显著正相关,尽管与前房深度(ACD)呈显著负相关(P = 0.005)。在性别之间或患有PEX或IFIS的患者中,ASM启动次数未观察到显著差异。在多变量分析中,ASM≥1显著预测更高的LOCS(优势比1.79,95%可信区间1.04 - 2.95),而更大的ACD降低了这种可能性(优势比0.311,95%可信区间0.100 - 0.960)。
随着晶状体硬度增加和年龄增长,ASM启动更频繁,而与浅前房相比,深前房会减少启动次数。晶状体硬度对ASM的影响大于前房深度,并且未发现PEX、IFIS与ASM之间存在显著相关性。