Parente F, Lazzaroni M, Imbimbo B P, Panza E, Ardizzone S, Bianchi Porro G
J Int Med Res. 1985;13(6):332-7. doi: 10.1177/030006058501300606.
The effectiveness of cimetropii bromidum (10 or 20 mg i.v.) as premedication for upper gastro-intestinal tract endoscopy was examined and compared with that of placebo in a double-blind crossover study involving 160 patients. The drug effects were assessed from the degree of opening of the pyloric sphincter and the endoscopist's rating of drug performance. The study showed that the effects of cimetropii bromidum differed highly significantly (p less than 0.0001) from those of placebo, on either count. No adverse effects were noted.
在一项涉及160名患者的双盲交叉研究中，研究了溴甲阿托品（静脉注射10或20毫克）作为上消化道内镜检查术前用药的有效性，并与安慰剂进行了比较。根据幽门括约肌的开放程度和内镜医师对药物效果的评分来评估药物效果。研究表明，无论从哪方面来看，溴甲阿托品的效果与安慰剂的效果都有极显著差异（p小于0.0001）。未观察到不良反应。
